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@ARTICLE{Adameyko:275838,
      author       = {Adameyko, Igor and Bakken, Trygve and Bhaduri, Aparna and
                      Chhatbar, Chintan and Filbin, Mariella G and Gate, David and
                      Hochgerner, Hannah and Kim, Chang Nam and Krull, Jordan and
                      La Manno, Gioele and Li, Qingyun and Linnarsson, Sten and
                      Ma, Qin and Mayer, Christian and Menon, Vilas and Nano,
                      Patricia and Prinz, Marco and Quake, Steve and Walsh,
                      Christopher A and Yang, Jin and Bayraktar, Omer Ali and
                      Gokce, Ozgun and Habib, Naomi and Konopka, Genevieve and
                      Liddelow, Shane A and Nowakowski, Tomasz J},
      title        = {{A}pplying single-cell and single-nucleus genomics to
                      studies of cellular heterogeneity and cell fate transitions
                      in the nervous system.},
      journal      = {Nature neuroscience},
      volume       = {27},
      number       = {12},
      issn         = {1097-6256},
      address      = {New York, NY},
      publisher    = {Nature America},
      reportid     = {DZNE-2025-00073},
      pages        = {2278 - 2291},
      year         = {2024},
      abstract     = {Single-cell and single-nucleus genomic approaches can
                      provide unbiased and multimodal insights. Here, we discuss
                      what constitutes a molecular cell atlas and how to leverage
                      single-cell omics data to generate hypotheses and gain
                      insights into cell transitions in development and disease of
                      the nervous system. We share points of reflection on what to
                      consider during study design and implementation as well as
                      limitations and pitfalls.},
      subtyp        = {Review Article},
      keywords     = {Animals / Humans / Cell Differentiation: genetics / Cell
                      Nucleus: metabolism / Cell Nucleus: genetics / Genomics:
                      methods / Nervous System: cytology / Nervous System:
                      metabolism / Single-Cell Analysis: methods},
      cin          = {AG Gokce},
      ddc          = {610},
      cid          = {I:(DE-2719)1013041},
      pnm          = {351 - Brain Function (POF4-351)},
      pid          = {G:(DE-HGF)POF4-351},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39627588},
      doi          = {10.1038/s41593-024-01827-9},
      url          = {https://pub.dzne.de/record/275838},
}