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@ARTICLE{Lewis:277541,
      author       = {Lewis, Karyn and Vallone, Valeria Fernandez and Dordevic,
                      Adam and Kern, Johannes and Stachelscheid, Harald and
                      Endres, Matthias and Boehmerle, Wolfgang and Huehnchen,
                      Petra and Schinke, Christian},
      title        = {{G}eneration of ten human induced pluripotent stem cell
                      lines (hi{PSC}s) from patients with and without
                      {C}hemotherapy-{I}nduced {P}eripheral {N}europathy ({CIPN})
                      and {P}ost {C}hemotherapy {C}ognitive {I}mpairment
                      ({PCCI}).},
      journal      = {Stem cell research},
      volume       = {84},
      issn         = {1873-5061},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DZNE-2025-00432},
      pages        = {103674 -},
      year         = {2025},
      abstract     = {Chemotherapy-induced peripheral neuropathy (CIPN) and
                      post-chemotherapy cognitive impairment (PCCI) represent
                      major side effects of chemotherapy. Using Sendai virus
                      vectors, ten hiPSC lines from patients who had undergone
                      chemotherapy and did or did not develop CIPN and PCCI were
                      generated. Each line was characterized to confirm markers of
                      the undifferentiated state, differentiation potential,
                      genomic integrity, identity verification and reprogramming
                      vector removal. These lines serve as a valuable resource to
                      create two disease models for 1) CIPN (hiPSC lines from five
                      patients with CIPN vs. five without CIPN) and 2) PCCI (hiPSC
                      lines from four patients with PCCI vs. five without PCCI).},
      keywords     = {Humans / Induced Pluripotent Stem Cells / Peripheral
                      Nervous System Diseases: chemically induced / Peripheral
                      Nervous System Diseases: pathology / Peripheral Nervous
                      System Diseases: therapy / Cognitive Dysfunction: chemically
                      induced / Male / Female / Cell Line / Middle Aged / Cell
                      Differentiation / Antineoplastic Agents: adverse effects /
                      Aged / Adult / Antineoplastic Agents (NLM Chemicals)},
      cin          = {AG Endres},
      ddc          = {570},
      cid          = {I:(DE-2719)1811005},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40015137},
      doi          = {10.1016/j.scr.2025.103674},
      url          = {https://pub.dzne.de/record/277541},
}