guest ::
| Home > Publications Database > Protocol for in vivo assessment of glucose control and insulin secretion and sensitivity in the pig. > print |
| Home > Publications Database > Protocol for in vivo assessment of glucose control and insulin secretion and sensitivity in the pig. > print |
| 001 | 278041 | ||
| 005 | 20260105131000.0 | ||
| 024 | 7 | _ | |a pmc:PMC12224880 |2 pmc |
| 024 | 7 | _ | |a 10.1016/j.xpro.2025.103774 |2 doi |
| 024 | 7 | _ | |a pmid:40249709 |2 pmid |
| 037 | _ | _ | |a DZNE-2025-00547 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 600 |
| 100 | 1 | _ | |a Eckstein, Yasmin |b 0 |
| 245 | _ | _ | |a Protocol for in vivo assessment of glucose control and insulin secretion and sensitivity in the pig. |
| 260 | _ | _ | |a Cambridge, MA |c 2025 |b Cell Press |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1745310238_32642 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a The pig is a valuable animal model in diabetes research; however, standardized protocols are essential for evaluating in vivo metabolism. Here, we present a protocol for in vivo assessment of glucose control and insulin secretion and sensitivity in the pig. We describe steps for catheter implantation, testing of intravenous glucose tolerance, performance of hyperinsulinemic-euglycemic clamps (HECs) and hyperglycemic clamps (HGCs), and blood processing. We then detail procedures for analysis of plasma glucose, insulin, glucagon, and C-peptide concentrations as well as data analysis. For complete details on the use and execution of this protocol, please refer to Renner et al.1 and Renner et al.2. |
| 536 | _ | _ | |a 899 - ohne Topic (POF4-899) |0 G:(DE-HGF)POF4-899 |c POF4-899 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de |
| 650 | _ | 7 | |a Biotechnology and bioengineering |2 Other |
| 650 | _ | 7 | |a Metabolism |2 Other |
| 650 | _ | 7 | |a Model Organisms |2 Other |
| 650 | _ | 2 | |a Animals |2 MeSH |
| 650 | _ | 2 | |a Swine |2 MeSH |
| 650 | _ | 2 | |a Insulin Secretion: physiology |2 MeSH |
| 650 | _ | 2 | |a Insulin: metabolism |2 MeSH |
| 650 | _ | 2 | |a Insulin: blood |2 MeSH |
| 650 | _ | 2 | |a Blood Glucose: metabolism |2 MeSH |
| 650 | _ | 2 | |a Blood Glucose: analysis |2 MeSH |
| 650 | _ | 2 | |a Glucose Clamp Technique: methods |2 MeSH |
| 650 | _ | 2 | |a Glucagon: blood |2 MeSH |
| 650 | _ | 2 | |a C-Peptide: blood |2 MeSH |
| 650 | _ | 2 | |a Glucose Tolerance Test: methods |2 MeSH |
| 700 | 1 | _ | |a Kessler, Barbara |b 1 |
| 700 | 1 | _ | |a Hinrichs, Arne |b 2 |
| 700 | 1 | _ | |a Novak, Istvan |b 3 |
| 700 | 1 | _ | |a von Thaden, Anne |0 P:(DE-2719)9000925 |b 4 |u dzne |
| 700 | 1 | _ | |a Lorenzen, Timo |b 5 |
| 700 | 1 | _ | |a Rathkolb, Birgit |b 6 |
| 700 | 1 | _ | |a Scholz, Armin |b 7 |
| 700 | 1 | _ | |a Blutke, Andreas |b 8 |
| 700 | 1 | _ | |a Koopmans, Sietse-Jan |b 9 |
| 700 | 1 | _ | |a de Angelis, Martin Hrabĕ |b 10 |
| 700 | 1 | _ | |a Christoffersen, Berit Østergaard |b 11 |
| 700 | 1 | _ | |a Wolf, Eckhard |b 12 |
| 700 | 1 | _ | |a Renner, Simone |b 13 |
| 773 | _ | _ | |a 10.1016/j.xpro.2025.103774 |g Vol. 6, no. 2, p. 103774 - |0 PERI:(DE-600)3053335-1 |n 2 |p 103774 |t STAR Protocols |v 6 |y 2025 |x 2666-1667 |
| 856 | 4 | _ | |y OpenAccess |u https://pub.dzne.de/record/278041/files/DZNE-2025-00547.pdf |
| 856 | 4 | _ | |y OpenAccess |x pdfa |u https://pub.dzne.de/record/278041/files/DZNE-2025-00547.pdf?subformat=pdfa |
| 909 | C | O | |o oai:pub.dzne.de:278041 |p openaire |p open_access |p VDB |p driver |p dnbdelivery |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 4 |6 P:(DE-2719)9000925 |
| 913 | 1 | _ | |a DE-HGF |b Programmungebundene Forschung |l ohne Programm |1 G:(DE-HGF)POF4-890 |0 G:(DE-HGF)POF4-899 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-800 |4 G:(DE-HGF)POF |v ohne Topic |x 0 |
| 914 | 1 | _ | |y 2025 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2024-12-31 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |d 2024-12-31 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1190 |2 StatID |b Biological Abstracts |d 2024-12-31 |
| 915 | _ | _ | |a Creative Commons Attribution CC BY 4.0 |0 LIC:(DE-HGF)CCBY4 |2 HGFVOC |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0112 |2 StatID |b Emerging Sources Citation Index |d 2024-12-31 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0501 |2 StatID |b DOAJ Seal |d 2023-04-12T14:51:27Z |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0500 |2 StatID |b DOAJ |d 2023-04-12T14:51:27Z |
| 915 | _ | _ | |a Fees |0 StatID:(DE-HGF)0700 |2 StatID |d 2024-12-31 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |d 2024-12-31 |
| 915 | _ | _ | |a OpenAccess |0 StatID:(DE-HGF)0510 |2 StatID |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b DOAJ : Anonymous peer review |d 2023-04-12T14:51:27Z |
| 915 | _ | _ | |a Article Processing Charges |0 StatID:(DE-HGF)0561 |2 StatID |d 2024-12-31 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2024-12-31 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2024-12-31 |
| 920 | 1 | _ | |0 I:(DE-2719)1140012 |k Mouse Facility (Munich) |l Mouse Facility (Munich) |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a UNRESTRICTED |
| 980 | _ | _ | |a I:(DE-2719)1140012 |
| 980 | 1 | _ | |a FullTexts |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|