Home > Publications Database > Fluid biomarkers unveil signatures of pathological aging. > print

001     278924
005     20250606100749.0
024 7 _ |a 10.1016/j.seizure.2024.05.019
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024 7 _ |a pmid:38871529
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024 7 _ |a 1059-1311
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024 7 _ |a 1532-2688
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037 _ _ |a DZNE-2025-00650
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Hansen, Niels
|b 0
245 _ _ |a Fluid biomarkers unveil signatures of pathological aging.
260 _ _ |a Oxford [u.a.]
|c 2025
|b Elsevier
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520 _ _ |a Aging is a multifaceted and highly varied process in the brain. Identifying aging biomarkers is one means of distinguishing pathological from physiological aging. The aim of this narrative review is to focus on two new developments in the field of fluid biomarkers and draw attention to this excellent tool for the early detection of potential brain pathologies that delay, alter, or enable physiological aging to become pathological. Pathological aging can lower the threshold for the development of specific diseases such as late-onset epilepsy. Fluid biomarkers can reveal pathological levels at an early stage and thus indicate disease processes in the brain that begin before symptoms develop; they thus differ from physiological aging.
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650 _ 7 |a Blood biomarkers
|2 Other
650 _ 7 |a Fluid biomarkers
|2 Other
650 _ 7 |a Inflammaging
|2 Other
650 _ 7 |a Late-onset epilepsy
|2 Other
650 _ 7 |a Neural autoantibodies
|2 Other
650 _ 7 |a Pathological and physiological aging
|2 Other
650 _ 7 |a Biomarkers
|2 NLM Chemicals
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Biomarkers: cerebrospinal fluid
|2 MeSH
650 _ 2 |a Aging: pathology
|2 MeSH
650 _ 2 |a Aging: cerebrospinal fluid
|2 MeSH
650 _ 2 |a Epilepsy: cerebrospinal fluid
|2 MeSH
650 _ 2 |a Brain: pathology
|2 MeSH
700 1 _ |a Wiltfang, Jens
|0 P:(DE-2719)2811317
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|e Last author
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773 _ _ |a 10.1016/j.seizure.2024.05.019
|g Vol. 128, p. 24 - 28
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856 4 _ |y OpenAccess
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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