%0 Journal Article
%A Kashani, Amir H
%A Berendschot, Tos T J M
%A Bonnin, Sophie
%A Sobrin, Lucia
%A De Jesus, Danilo Andrade
%A Brea, Luisa Sanchez
%A Martinez, Ana Collazo
%A Raman, Rajiv
%A de Vries, Victor A
%A Huang, Haifan
%A consortium, E3
%A MacGillivray, Tom
%A Ramdas, Wishal D
%A van der Heide, Frank C T
%T Retinal optical coherence tomography angiography imaging in population studies for study of microvascular dysfunction in Alzheimer's disease and related dementias.
%J Alzheimer's and dementia
%V 21
%N 6
%@ 1552-5260
%C Hoboken, NJ
%I Wiley
%M DZNE-2025-00661
%P e70252
%D 2025
%X Widespread use of retinal optical coherence tomography angiography (OCT-A) imaging requires methodological and analytical consensus to ensure reproducible and accurate results in epidemiological studies on Alzheimer's disease and related dementias (ADRD).A consensus framework for assessment of fovea-centered 3 × 3-mm and 6 × 6-mm OCT-A image quality was developed, and reproducibility was reported. Agreement was assessed for overall image quality and image quality relevant for vessel density (VD) quantification and foveal avascular zone (FAZ) metrics. An analytic framework was also developed.Intergrader agreements for overall 3 × 3 mm image quality and quantitative assessment of VD and FAZ ranged between 71
%K Humans
%K Tomography, Optical Coherence: methods
%K Alzheimer Disease: diagnostic imaging
%K Retinal Vessels: diagnostic imaging
%K Reproducibility of Results
%K Fluorescein Angiography: methods
%K Female
%K Dementia: diagnostic imaging
%K Male
%K Aged
%K Alzheimer's disease and related dementias (Other)
%K accelerated cognitive ageing (Other)
%K epidemiology (Other)
%K harmonization (Other)
%K imaging (Other)
%K microvascular dysfunction (Other)
%K neurodegenerative disease (Other)
%K optical coherence tomography angiography (Other)
%K population‐based study (Other)
%K retinal imaging (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40457754
%R 10.1002/alz.70252
%U https://pub.dzne.de/record/278997