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@ARTICLE{Boura:279175,
      author       = {Boura, Iro and Poplawska-Domaszewicz, Karolina and Spanaki,
                      Cleanthe and Chen, Rosabel and Urso, Daniele and van Coller,
                      Riaan and Storch, Alexander and Chaudhuri, Kallol Ray},
      title        = {{N}on-{M}otor {F}luctuations in {P}arkinson’s {D}isease:
                      {U}nderdiagnosed {Y}et {I}mportant},
      journal      = {Journal of movement disorders},
      volume       = {18},
      number       = {1},
      issn         = {2005-940X},
      address      = {Seoul},
      publisher    = {Korean Movement Disorder Society},
      reportid     = {DZNE-2025-00703},
      pages        = {1 - 16},
      year         = {2025},
      abstract     = {Non-motor fluctuations (NMFs) in Parkinson's disease (PD)
                      significantly affect patients' well-being. Despite being
                      identified over two decades ago, NMFs remain largely
                      underrecognized, undertreated, and poorly understood. While
                      they are often temporally associated with motor fluctuations
                      (MFs) and can share common risk factors and pathophysiologic
                      mechanisms, NMFs and MFs are currently considered distinct
                      entities. The prevalence and severity of NMFs, often
                      categorized into neuropsychiatric, sensory, and autonomic
                      subtypes, vary significantly across studies due to the
                      heterogeneous PD populations screened and the diverse
                      evaluation tools applied. The consistent negative impact of
                      NMFs on PD patients' quality of life underscores the
                      importance of further investigations via focused and
                      controlled studies, validated assessment instruments and
                      novel digital technologies. High-quality research is
                      essential to illuminate the complex pathophysiology and
                      clinical nuances of NMFs, ultimately enhancing clinicians'
                      diagnostic and treatment options in routine clinical
                      practice.},
      keywords     = {Advanced (Other) / Fluctuations (Other) / Non-motor (Other)
                      / Parkinson’s disease (Other) / Therapy (Other)},
      cin          = {AG Storch},
      ddc          = {610},
      cid          = {I:(DE-2719)5000014},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      doi          = {10.14802/jmd.24227},
      url          = {https://pub.dzne.de/record/279175},
}