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| Home > Publications Database > Dataset: RNA-seq of human post-mortem brain tissue of the frontal lobe from patients with FTD and healthy controls |
| Home > Publications Database > Dataset: RNA-seq of human post-mortem brain tissue of the frontal lobe from patients with FTD and healthy controls |
| Dataset | DZNE-2025-00793 |
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2023
ArrayExpress
Abstract: Understanding the molecular mechanisms underlying frontotemporal dementia (FTD) is essential for the development of successful therapies. Systematic studies on human post-mortem brain tissue of patients with genetic subtypes of FTD are currently lacking. The Risk and Modyfing Factors of Frontotemporal Dementia (RiMod-FTD) consortium therefore has generated multi-omics datasets for genetic subtypes of FTD to identify common and distinct molecular mechanisms disturbed in disease. This experiment contains data from RNA-sequencing of human post-mortem brain tissue of the frontal lobe from patients with FTD caused by mutations in GRN, MAPT or C9orf72 and healthy controls.
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