TY - CHART
AU - Müller, Stephan A
AU - Lichtenthaler, Stefan
TI - Dataset: Proteome analysis of amniotic fluid from fetuses with myelomeningocele from singleton pregnancies
PB - PRoteomics IDEntifications Database
M1 - DZNE-2025-00805
PY - 2025
AB - Despite numerous studies on fetal therapy for myelomeningoceles (MMC), the pathophysiology of this malformation remains poorly understood. This study aimed to analyze the biochemical profile and proteome of amniotic fluid (AF) supernatants from MMC fetuses to explore the prenatal pathophysiology. Proteome analysis was conducted in 18 MMC and 18 healthy singleton fetuses, as well as in 5 dichorionic pregnancies with MMC fetuses and their healthy co-twins. ELISA tests were used to validate proteome results. Biochemical analysis revealed anal incontinence in 37
LB - PUB:(DE-HGF)32
UR - https://pub.dzne.de/record/279478
ER -