000279480 001__ 279480
000279480 005__ 20250710100950.0
000279480 037__ $$aDZNE-2025-00807
000279480 1001_ $$0P:(DE-2719)2810938$$aMüller, Stephan A$$b0$$udzne
000279480 245__ $$aDataset: Mouse CSF analysis of 3, 6, and 12 months old mice in comparison to human CSF
000279480 260__ $$bPRoteomics IDEntifications Database$$c2025
000279480 3367_ $$2BibTeX$$aMISC
000279480 3367_ $$0PUB:(DE-HGF)32$$2PUB:(DE-HGF)$$aDataset$$bdataset$$mdataset$$s1752049627_17545
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000279480 520__ $$aMice are the most commonly used preclinical animal model, but protein analytics of murine cerebrospinal fluid (CSF) remains challenging because of low CSF volume (often <10 µl) and frequent blood contaminations. We developed an improved CSF sampling method that allows routine collection of increased volumes (20-30 µl) of pure CSF from individual mice, enabling multiple protein analytical assays from a single sample. Here, we have analysed the CSF of 3, 6, and 12 months old wild-type mice. Additionally, we collected murine CSF of the same mice at 3 and 6 months of age to compare repeated and single CSF sampling. Furthermore, we analysed human CSF samples as a reference.
000279480 536__ $$0G:(DE-HGF)POF4-352$$a352 - Disease Mechanisms (POF4-352)$$cPOF4-352$$fPOF IV$$x0
000279480 7001_ $$0P:(DE-2719)2181459$$aLichtenthaler, Stefan$$b1$$udzne
000279480 7870_ $$0DZNE-2025-00672$$aLourbopoulos, Athanasios et.al.$$dBethesda, Md. : The American Society for Biochemistry and Molecular Biology, 2025$$iRelatedTo$$r$$tAn Improved Method for Sampling and Quantitative Protein Analytics of Cerebrospinal Fluid of Individual Mice.
000279480 8564_ $$uhttps://wwwdev.ebi.ac.uk/pride/archive/projects/PXD053698
000279480 909CO $$ooai:pub.dzne.de:279480$$pVDB
000279480 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2810938$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b0$$kDZNE
000279480 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2181459$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE
000279480 9131_ $$0G:(DE-HGF)POF4-352$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vDisease Mechanisms$$x0
000279480 9141_ $$y2025
000279480 9201_ $$0I:(DE-2719)1110006$$kAG Lichtenthaler$$lNeuroproteomics$$x0
000279480 980__ $$adataset
000279480 980__ $$aVDB
000279480 980__ $$aI:(DE-2719)1110006
000279480 980__ $$aUNRESTRICTED