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@MISC{Mller:279480,
author = {Müller, Stephan A and Lichtenthaler, Stefan},
title = {{D}ataset: {M}ouse {CSF} analysis of 3, 6, and 12 months
old mice in comparison to human {CSF}},
publisher = {PRoteomics IDEntifications Database},
reportid = {DZNE-2025-00807},
year = {2025},
abstract = {Mice are the most commonly used preclinical animal model,
but protein analytics of murine cerebrospinal fluid (CSF)
remains challenging because of low CSF volume (often <10
µl) and frequent blood contaminations. We developed an
improved CSF sampling method that allows routine collection
of increased volumes (20-30 µl) of pure CSF from individual
mice, enabling multiple protein analytical assays from a
single sample. Here, we have analysed the CSF of 3, 6, and
12 months old wild-type mice. Additionally, we collected
murine CSF of the same mice at 3 and 6 months of age to
compare repeated and single CSF sampling. Furthermore, we
analysed human CSF samples as a reference.},
cin = {AG Lichtenthaler},
cid = {I:(DE-2719)1110006},
pnm = {352 - Disease Mechanisms (POF4-352)},
pid = {G:(DE-HGF)POF4-352},
typ = {PUB:(DE-HGF)32},
url = {https://pub.dzne.de/record/279480},
}