Home > Publications Database > Dataset: Mouse CSF analysis of 3, 6, and 12 months old mice in comparison to human CSF > print

001     279480
005     20250710100950.0
037 _ _ |a DZNE-2025-00807
100 1 _ |a Müller, Stephan A
|0 P:(DE-2719)2810938
|b 0
|u dzne
245 _ _ |a Dataset: Mouse CSF analysis of 3, 6, and 12 months old mice in comparison to human CSF
260 _ _ |c 2025
|b PRoteomics IDEntifications Database
336 7 _ |a MISC
|2 BibTeX
336 7 _ |a Dataset
|b dataset
|m dataset
|0 PUB:(DE-HGF)32
|s 1752049627_17545
|2 PUB:(DE-HGF)
336 7 _ |a Chart or Table
|0 26
|2 EndNote
336 7 _ |a Dataset
|2 DataCite
336 7 _ |a DATA_SET
|2 ORCID
336 7 _ |a ResearchData
|2 DINI
520 _ _ |a Mice are the most commonly used preclinical animal model, but protein analytics of murine cerebrospinal fluid (CSF) remains challenging because of low CSF volume (often <10 µl) and frequent blood contaminations. We developed an improved CSF sampling method that allows routine collection of increased volumes (20-30 µl) of pure CSF from individual mice, enabling multiple protein analytical assays from a single sample. Here, we have analysed the CSF of 3, 6, and 12 months old wild-type mice. Additionally, we collected murine CSF of the same mice at 3 and 6 months of age to compare repeated and single CSF sampling. Furthermore, we analysed human CSF samples as a reference.
536 _ _ |a 352 - Disease Mechanisms (POF4-352)
|0 G:(DE-HGF)POF4-352
|c POF4-352
|f POF IV
|x 0
700 1 _ |a Lichtenthaler, Stefan
|0 P:(DE-2719)2181459
|b 1
|u dzne
787 0 _ |a Lourbopoulos, Athanasios et.al.
|d Bethesda, Md. : The American Society for Biochemistry and Molecular Biology, 2025
|i RelatedTo
|0 DZNE-2025-00672
|r
|t An Improved Method for Sampling and Quantitative Protein Analytics of Cerebrospinal Fluid of Individual Mice.
856 4 _ |u https://wwwdev.ebi.ac.uk/pride/archive/projects/PXD053698
909 C O |o oai:pub.dzne.de:279480
|p VDB
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 0
|6 P:(DE-2719)2810938
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 1
|6 P:(DE-2719)2181459
913 1 _ |a DE-HGF
|b Gesundheit
|l Neurodegenerative Diseases
|1 G:(DE-HGF)POF4-350
|0 G:(DE-HGF)POF4-352
|3 G:(DE-HGF)POF4
|2 G:(DE-HGF)POF4-300
|4 G:(DE-HGF)POF
|v Disease Mechanisms
|x 0
914 1 _ |y 2025
920 1 _ |0 I:(DE-2719)1110006
|k AG Lichtenthaler
|l Neuroproteomics
|x 0
980 _ _ |a dataset
980 _ _ |a VDB
980 _ _ |a I:(DE-2719)1110006
980 _ _ |a UNRESTRICTED

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