%0 Chart or Table
%A Gloeckner, Christian Johannes
%T Dataset: Analysis of conformational changes induced by binding of allosteric nanobodies to a bacterial LRRK2 homologue by CX-MS
%I PRoteomics IDEntifications Database
%M DZNE-2025-00814
%D 2024
%X As part of an in-depth characterization of nanobodies directed against the Chlorobium tepidum protein CtRoco, a bacterial LRRK2 homologue, chemical crosslinking combined with mass spectrometry (CX-MS) was performed. Two allosteric nanobodies binding to two different epitopes in the LRR and the Roc domain of CtRoco, respectively were analysed using the CID-cleavable crosslinker disuccinimidyl sulfoxide (DSSO).
%F PUB:(DE-HGF)32
%9 Dataset
%U https://pub.dzne.de/record/279487