000279487 001__ 279487
000279487 005__ 20250710100950.0
000279487 037__ $$aDZNE-2025-00814
000279487 1001_ $$0P:(DE-2719)2811291$$aGloeckner, Christian Johannes$$b0$$udzne
000279487 245__ $$aDataset: Analysis of conformational changes induced by binding of allosteric nanobodies to a bacterial LRRK2 homologue by CX-MS
000279487 260__ $$bPRoteomics IDEntifications Database$$c2024
000279487 3367_ $$2BibTeX$$aMISC
000279487 3367_ $$0PUB:(DE-HGF)32$$2PUB:(DE-HGF)$$aDataset$$bdataset$$mdataset$$s1752048055_17545
000279487 3367_ $$026$$2EndNote$$aChart or Table
000279487 3367_ $$2DataCite$$aDataset
000279487 3367_ $$2ORCID$$aDATA_SET
000279487 3367_ $$2DINI$$aResearchData
000279487 520__ $$aAs part of an in-depth characterization of nanobodies directed against the Chlorobium tepidum protein CtRoco, a bacterial LRRK2 homologue, chemical crosslinking combined with mass spectrometry (CX-MS) was performed. Two allosteric nanobodies binding to two different epitopes in the LRR and the Roc domain of CtRoco, respectively were analysed using the CID-cleavable crosslinker disuccinimidyl sulfoxide (DSSO).
000279487 536__ $$0G:(DE-HGF)POF4-352$$a352 - Disease Mechanisms (POF4-352)$$cPOF4-352$$fPOF IV$$x0
000279487 7870_ $$0DZNE-2024-00514$$aGalicia, Christian et.al.$$dCambridge : eLife Sciences Publications, 2024$$iRelatedTo$$r$$tStructural insights into the GTP-driven monomerization and activation of a bacterial LRRK2 homolog using allosteric nanobodies.
000279487 8564_ $$uhttps://wwwdev.ebi.ac.uk/pride/archive/projects/PXD046634
000279487 909CO $$ooai:pub.dzne.de:279487$$pVDB
000279487 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2811291$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b0$$kDZNE
000279487 9131_ $$0G:(DE-HGF)POF4-352$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vDisease Mechanisms$$x0
000279487 9201_ $$0I:(DE-2719)1210007$$kAG Gloeckner$$lFunctional Neuroproteomics and Translational Biomarkers in Neurodegenerative Diseases$$x0
000279487 980__ $$adataset
000279487 980__ $$aVDB
000279487 980__ $$aI:(DE-2719)1210007
000279487 980__ $$aUNRESTRICTED