TY  - CHART
AU  - Gloeckner, Christian Johannes
TI  - Dataset: Analysis of conformational changes induced by binding of allosteric nanobodies to a bacterial LRRK2 homologue by CX-MS
PB  - PRoteomics IDEntifications Database
M1  - DZNE-2025-00814
PY  - 2024
AB  - As part of an in-depth characterization of nanobodies directed against the Chlorobium tepidum protein CtRoco, a bacterial LRRK2 homologue, chemical crosslinking combined with mass spectrometry (CX-MS) was performed. Two allosteric nanobodies binding to two different epitopes in the LRR and the Roc domain of CtRoco, respectively were analysed using the CID-cleavable crosslinker disuccinimidyl sulfoxide (DSSO).
LB  - PUB:(DE-HGF)32
UR  - https://pub.dzne.de/record/279487
ER  -