Patent

DZNE-2025-00852

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Activators of protein phosphatase 5

Groll, M. ; Richter, K. ; Haslbeck, V. ; Striggow, F.DZNE* ; Martin, H. ; Schmidt, W.DZNE* ; Weiwad, M. ; Fischer, G.

2015

Patent No.: EP-2878677-A1; EP2878677A1

Abstract: The present invention relates to compounds that show a positive result in a phosphatase activation assay with protein phosphatase 5 according to the invention, to compounds that bind in an in vitro binding assay to a certain region of the amino acid sequence of protein phosphatase 5, as well as to compounds that show a positive result in a phosphatase activation assay with protein phosphatase 5 according to the invention and bind in an in vitro binding assay to a certain region of the amino acid sequence of protein phosphatase 5. The present invention also relates to pharmaceutical compositions comprising one or more of such compounds, to methods of using such a compound, and to methods of screening for compounds that activate protein phosphatase 5.

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Contributing Institute(s):

1. Neurodegeneration and Intervention Strategies (AG Striggow)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)

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