000279885 001__ 279885 000279885 005__ 20250716101215.0 000279885 013__ $$aEP-2878677-A1 000279885 0247_ $$2Patent$$aEP2878677A1 000279885 037__ $$aDZNE-2025-00852 000279885 1001_ $$0P:(DE-HGF)0$$aGroll, Michael$$b0 000279885 245__ $$aActivators of protein phosphatase 5 000279885 260__ $$c2015 000279885 3367_ $$2ORCID$$aPATENT 000279885 3367_ $$0PUB:(DE-HGF)23$$2PUB:(DE-HGF)$$aPatent$$bpatent$$mpatent$$s1752572536_17592 000279885 3367_ $$2DRIVER$$apatent 000279885 3367_ $$2BibTeX$$aTECHREPORT 000279885 3367_ $$015$$2EndNote$$aPatent 000279885 3367_ $$2DataCite$$aPatent 000279885 520__ $$aThe present invention relates to compounds that show a positive result in a phosphatase activation assay with protein phosphatase 5 according to the invention, to compounds that bind in an in vitro binding assay to a certain region of the amino acid sequence of protein phosphatase 5, as well as to compounds that show a positive result in a phosphatase activation assay with protein phosphatase 5 according to the invention and bind in an in vitro binding assay to a certain region of the amino acid sequence of protein phosphatase 5. The present invention also relates to pharmaceutical compositions comprising one or more of such compounds, to methods of using such a compound, and to methods of screening for compounds that activate protein phosphatase 5. 000279885 536__ $$0G:(DE-HGF)POF4-899$$a899 - ohne Topic (POF4-899)$$cPOF4-899$$fPOF IV$$x0 000279885 7001_ $$0P:(DE-HGF)0$$aRichter, Klaus$$b1 000279885 7001_ $$0P:(DE-HGF)0$$aHaslbeck, Veronika$$b2 000279885 7001_ $$0P:(DE-2719)9000420$$aStriggow, Frank$$b3 000279885 7001_ $$0P:(DE-HGF)0$$aMartin, Helmuth$$b4 000279885 7001_ $$0P:(DE-2719)9000421$$aSchmidt, Werner$$b5 000279885 7001_ $$0P:(DE-HGF)0$$aWeiwad, Matthias$$b6 000279885 7001_ $$0P:(DE-HGF)0$$aFischer, Gunter$$b7 000279885 8564_ $$uhttps://pub.dzne.de/record/279885/files/DZNE-2025-00852_Restricted.pdf 000279885 8564_ $$uhttps://pub.dzne.de/record/279885/files/DZNE-2025-00852_Restricted.pdf?subformat=pdfa$$xpdfa 000279885 909CO $$ooai:pub.dzne.de:279885$$pVDB 000279885 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9000420$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b3$$kDZNE 000279885 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9000421$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b5$$kDZNE 000279885 9131_ $$0G:(DE-HGF)POF4-899$$1G:(DE-HGF)POF4-890$$2G:(DE-HGF)POF4-800$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$vohne Topic$$x0 000279885 9201_ $$0I:(DE-2719)5000045$$kAG Striggow$$lNeurodegeneration and Intervention Strategies$$x0 000279885 980__ $$apatent 000279885 980__ $$aVDB 000279885 980__ $$aI:(DE-2719)5000045 000279885 980__ $$aUNRESTRICTED