TY  - JOUR
AU  - Barczuk, Julia
AU  - Milovanovic, Dragomir
TI  - It must have been network (percolation for the synaptic function).
JO  - Molecular cell
VL  - 85
IS  - 17
SN  - 1097-2765
CY  - [Cambridge, Mass.]
PB  - Cell Press
M1  - DZNE-2025-01079
SP  - 3203 - 3205
PY  - 2025
AB  - How does synaptic wiring depend on receptor clustering, scaffold networks, and signaling cohorts? In a recent study in Molecular Cell, Jia et al.1 demonstrate that targeting the interaction strength between the scaffold proteins, rather than the total amount of each protein component, modulates the signal propagation across the protein network.
KW  - Synapses: physiology
KW  - Synapses: metabolism
KW  - Animals
KW  - Signal Transduction
KW  - Humans
KW  - Synaptic Transmission
LB  - PUB:(DE-HGF)16
C6  - pmid:40912242
DO  - DOI:10.1016/j.molcel.2025.08.013
UR  - https://pub.dzne.de/record/281120
ER  -