Journal Article

DZNE-2025-01079

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png It must have been network (percolation for the synaptic function).

Barczuk, J. (First author)DZNE* ; Milovanovic, D. (Last author)DZNE*

2025
Cell Press [Cambridge, Mass.]

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Please use a persistent id in citations: doi:10.1016/j.molcel.2025.08.013

Abstract: How does synaptic wiring depend on receptor clustering, scaffold networks, and signaling cohorts? In a recent study in Molecular Cell, Jia et al.1 demonstrate that targeting the interaction strength between the scaffold proteins, rather than the total amount of each protein component, modulates the signal propagation across the protein network.

Keyword(s): Synapses: physiology (MeSH) ; Synapses: metabolism (MeSH) ; Animals (MeSH) ; Signal Transduction (MeSH) ; Humans (MeSH) ; Synaptic Transmission (MeSH)

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Contributing Institute(s):

1. Molecular Neuroscience (AG Milovanovic (Berlin))

Research Program(s):

1. 351 - Brain Function (POF4-351) (POF4-351)

Appears in the scientific report 2025

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Database coverage:
; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 15 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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