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000281355 041__ $$aEnglish
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000281355 1001_ $$00000-0001-6554-1033$$aCesari, Matteo$$b0
000281355 245__ $$aIsolated REM Sleep Behaviour Disorder-Is Screening Possible?
000281355 260__ $$aOxford [u.a.]$$bWiley-Blackwell$$c2025
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000281355 520__ $$aRapid eye movement (REM) sleep behaviour disorder (RBD) is a parasomnia characterised by the loss of muscle atonia during REM sleep and dream-enacting behaviours. In its isolated form (iRBD) it is widely recognised as an early stage of alpha-synucleinopathies. Early identification of patients with iRBD allows for timely interventions, risk mitigation and potential inclusion in clinical trials aimed at disease modification. Effective screening tools, including questionnaires, automatic analyses of video-polysomnography, actigraphy, nearables and biological markers, can facilitate diagnosis and monitoring. Incorporating routine screening into clinical practice may enhance early detection and improve long-term patient outcomes. This manuscript presents the latest developments in screening tools for the identification of patients with iRBD and discusses their advantages and drawbacks, highlighting paths for future research and applications.
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000281355 650_7 $$2Other$$aRBD
000281355 650_7 $$2Other$$aiRBD
000281355 650_7 $$2Other$$aprodromal alpha‐synucleinopathy
000281355 650_7 $$2Other$$ascreening tool
000281355 650_2 $$2MeSH$$aHumans
000281355 650_2 $$2MeSH$$aREM Sleep Behavior Disorder: diagnosis
000281355 650_2 $$2MeSH$$aPolysomnography
000281355 650_2 $$2MeSH$$aActigraphy
000281355 650_2 $$2MeSH$$aSurveys and Questionnaires
000281355 650_2 $$2MeSH$$aMass Screening: methods
000281355 7001_ $$aBrink-Kjaer, Andreas$$b1
000281355 7001_ $$aDuring, Emmanuel$$b2
000281355 7001_ $$00000-0002-6029-2450$$aGanglberger, Wolfgang$$b3
000281355 7001_ $$aGnarra, Oriella$$b4
000281355 7001_ $$aHuang, Bei$$b5
000281355 7001_ $$0P:(DE-2719)9003277$$aSommerauer, Michael$$b6$$udzne
000281355 7001_ $$aRatti, Pietro Luca$$b7
000281355 7001_ $$00000-0002-9420-4922$$aRechichi, Irene$$b8
000281355 7001_ $$00000-0002-5745-5474$$aWing, Yun Kwok$$b9
000281355 7001_ $$00000-0003-4259-8824$$aStefani, Ambra$$b10
000281355 773__ $$0PERI:(DE-600)2007459-1$$a10.1111/jsr.70109$$gVol. 34, no. 5, p. e70109$$n5$$pe70109$$tJournal of sleep research$$v34$$x0962-1105$$y2025
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