000281804 001__ 281804
000281804 005__ 20251023092610.0
000281804 0247_ $$2doi$$a10.5281/ZENODO.15348780
000281804 0247_ $$2doi$$a10.5281/zenodo.15348780
000281804 037__ $$aDZNE-2025-01190
000281804 041__ $$aEnglish
000281804 1001_ $$00009-0007-0800-2309$$ade Oliveira Pires, Leonor$$b0
000281804 245__ $$aDataset: Computational Modeling and Validation Data for Trans-spinal Direct Current Stimulation (tsDCS) in SOD1 Mice
000281804 260__ $$bZenodo$$c2025
000281804 3367_ $$2BibTeX$$aMISC
000281804 3367_ $$0PUB:(DE-HGF)32$$2PUB:(DE-HGF)$$aDataset$$bdataset$$mdataset$$s1761204352_5633
000281804 3367_ $$026$$2EndNote$$aChart or Table
000281804 3367_ $$2DataCite$$aDataset
000281804 3367_ $$2ORCID$$aDATA_SET
000281804 3367_ $$2DINI$$aResearchData
000281804 520__ $$aThis dataset provides a multimodal collection of data acquired and generated in the context of an investigation that aims to provide a comprehensive computational model that predicts the electric fields (EF) induced by tsDCS intervention in SOD1 mice. It includes a .zip archive for each of the following: Full-body MRI data in DICOM format 3D anatomical models and simulation files related to tsDCS Electrophysiological recordings and analysis scripts validating model predictions 1. Magnetic Resonance Imaging (MRI) Data- Format: DICOM (.dcm)- Modality: MRI, T2-weighted- Acquisition Sequence: FLASH- Anatomical Region: Full-body (mouse)- Slices: 165 axial slices- Includes README file with more detailed information 2. Computational Simulation & Anatomical Models - Formats: >*.mph and .mphtxt COMSOL model files (mesh and simulation setup) > STL-format 3D anatomical models for computational modeling - Anatomical Structures in STL Files: > Heart, Intestines, Kidneys, Liver, Lungs, Pancreas, Spleen, Stomach > Skull and Brain > Full spine (including GM, WM, CSF, dura mater, vertebrae, IVDs, and surrounding fat) - Includes README file with more detailed information 3. Electrophysiological Validation Data - Formats: > Spike Recordings (.smr): Raw electrophysiological recordings (openable in Spike2) > RStudio Script (.R): For statistical analysis and visualization of electrophysiological results > Voltage Deflection Measurements (.xlsx): Tabulated results of evoked voltage by electrode distance, depth, tsDCS configuration, and current intensity
000281804 536__ $$0G:(DE-HGF)POF4-352$$a352 - Disease Mechanisms (POF4-352)$$cPOF4-352$$fPOF IV$$x0
000281804 588__ $$aDataset connected to DataCite
000281804 650_7 $$2Other$$acomputational model
000281804 650_7 $$2Other$$aspinal cord
000281804 650_7 $$2Other$$aamyotrophic lateral sclerosis
000281804 650_7 $$2Other$$ain vivo
000281804 650_7 $$2Other$$aelectrophysiology
000281804 650_7 $$2Other$$amagnetic resonance imaging
000281804 650_7 $$2Other$$amice
000281804 7001_ $$00009-0008-0521-6851$$aWasicki, Bartosz$$b1
000281804 7001_ $$00000-0003-2287-6495$$aAbaei, Alireza$$b2
000281804 7001_ $$0P:(DE-2719)9001282$$aScekic-Zahirovic, Jelena$$b3
000281804 7001_ $$0P:(DE-2719)2812851$$aroselli, francesco$$b4
000281804 7001_ $$00000-0002-0576-8364$$aFernandes, Sofia Rita$$b5
000281804 7001_ $$00000-0002-2656-9655$$aBączyk, Marcin$$b6
000281804 773__ $$a10.5281/zenodo.15348780
000281804 7870_ $$0DZNE-2025-01137$$ade Oliveira Pires, L. et.al.$$dAmsterdam [u.a.] : Elsevier Science, 2025$$iRelatedTo$$r$$tA computational model of tsDCS effects in SOD1 mice: from MRI-based design to validation.
000281804 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9001282$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b3$$kDZNE
000281804 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2812851$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b4$$kDZNE
000281804 9131_ $$0G:(DE-HGF)POF4-352$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vDisease Mechanisms$$x0
000281804 9141_ $$y2025
000281804 9201_ $$0I:(DE-2719)1910001$$kAG Roselli$$lMetabolic Changes in Neurodegeneration$$x0
000281804 980__ $$adataset
000281804 980__ $$aEDITORS
000281804 980__ $$aVDBINPRINT
000281804 980__ $$aI:(DE-2719)1910001
000281804 980__ $$aUNRESTRICTED