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@MISC{deOliveiraPires:281804,
author = {de Oliveira Pires, Leonor and Wasicki, Bartosz and Abaei,
Alireza and Scekic-Zahirovic, Jelena and roselli, francesco
and Fernandes, Sofia Rita and Bączyk, Marcin},
title = {{D}ataset: {C}omputational {M}odeling and {V}alidation
{D}ata for {T}rans-spinal {D}irect {C}urrent {S}timulation
(ts{DCS}) in {SOD}1 {M}ice},
publisher = {Zenodo},
reportid = {DZNE-2025-01190},
year = {2025},
abstract = {This dataset provides a multimodal collection of data
acquired and generated in the context of an investigation
that aims to provide a comprehensive computational model
that predicts the electric fields (EF) induced by tsDCS
intervention in SOD1 mice. It includes a .zip archive for
each of the following: Full-body MRI data in DICOM format 3D
anatomical models and simulation files related to tsDCS
Electrophysiological recordings and analysis scripts
validating model predictions 1. Magnetic Resonance Imaging
(MRI) Data- Format: DICOM (.dcm)- Modality: MRI,
T2-weighted- Acquisition Sequence: FLASH- Anatomical Region:
Full-body (mouse)- Slices: 165 axial slices- Includes README
file with more detailed information 2. Computational
Simulation $\&$ Anatomical Models - Formats: >*.mph and
.mphtxt COMSOL model files (mesh and simulation setup) >
STL-format 3D anatomical models for computational modeling -
Anatomical Structures in STL Files: > Heart, Intestines,
Kidneys, Liver, Lungs, Pancreas, Spleen, Stomach > Skull and
Brain > Full spine (including GM, WM, CSF, dura mater,
vertebrae, IVDs, and surrounding fat) - Includes README file
with more detailed information 3. Electrophysiological
Validation Data - Formats: > Spike Recordings (.smr): Raw
electrophysiological recordings (openable in Spike2) >
RStudio Script (.R): For statistical analysis and
visualization of electrophysiological results > Voltage
Deflection Measurements (.xlsx): Tabulated results of evoked
voltage by electrode distance, depth, tsDCS configuration,
and current intensity},
keywords = {computational model (Other) / spinal cord (Other) /
amyotrophic lateral sclerosis (Other) / in vivo (Other) /
electrophysiology (Other) / magnetic resonance imaging
(Other) / mice (Other)},
cin = {AG Roselli},
cid = {I:(DE-2719)1910001},
pnm = {352 - Disease Mechanisms (POF4-352)},
pid = {G:(DE-HGF)POF4-352},
typ = {PUB:(DE-HGF)32},
doi = {10.5281/zenodo.15348780},
url = {https://pub.dzne.de/record/281804},
}