Home > Publications Database > Dataset: Computational Modeling and Validation Data for Trans-spinal Direct Current Stimulation (tsDCS) in SOD1 Mice > print

001     281804
005     20251113102918.0
024 7 _ |a 10.5281/ZENODO.15348780
|2 doi
024 7 _ |a 10.5281/zenodo.15348780
|2 doi
037 _ _ |a DZNE-2025-01190
041 _ _ |a English
100 1 _ |a de Oliveira Pires, Leonor
|0 0009-0007-0800-2309
|b 0
245 _ _ |a Dataset: Computational Modeling and Validation Data for Trans-spinal Direct Current Stimulation (tsDCS) in SOD1 Mice
260 _ _ |c 2025
|b Zenodo
336 7 _ |a MISC
|2 BibTeX
336 7 _ |a Dataset
|b dataset
|m dataset
|0 PUB:(DE-HGF)32
|s 1762949751_29015
|2 PUB:(DE-HGF)
336 7 _ |a Chart or Table
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336 7 _ |a Dataset
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336 7 _ |a DATA_SET
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336 7 _ |a ResearchData
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520 _ _ |a This dataset provides a multimodal collection of data acquired and generated in the context of an investigation that aims to provide a comprehensive computational model that predicts the electric fields (EF) induced by tsDCS intervention in SOD1 mice. It includes a .zip archive for each of the following: Full-body MRI data in DICOM format 3D anatomical models and simulation files related to tsDCS Electrophysiological recordings and analysis scripts validating model predictions 1. Magnetic Resonance Imaging (MRI) Data- Format: DICOM (.dcm)- Modality: MRI, T2-weighted- Acquisition Sequence: FLASH- Anatomical Region: Full-body (mouse)- Slices: 165 axial slices- Includes README file with more detailed information 2. Computational Simulation & Anatomical Models - Formats: >*.mph and .mphtxt COMSOL model files (mesh and simulation setup) > STL-format 3D anatomical models for computational modeling - Anatomical Structures in STL Files: > Heart, Intestines, Kidneys, Liver, Lungs, Pancreas, Spleen, Stomach > Skull and Brain > Full spine (including GM, WM, CSF, dura mater, vertebrae, IVDs, and surrounding fat) - Includes README file with more detailed information 3. Electrophysiological Validation Data - Formats: > Spike Recordings (.smr): Raw electrophysiological recordings (openable in Spike2) > RStudio Script (.R): For statistical analysis and visualization of electrophysiological results > Voltage Deflection Measurements (.xlsx): Tabulated results of evoked voltage by electrode distance, depth, tsDCS configuration, and current intensity
536 _ _ |a 352 - Disease Mechanisms (POF4-352)
|0 G:(DE-HGF)POF4-352
|c POF4-352
|f POF IV
|x 0
588 _ _ |a Dataset connected to DataCite
650 _ 7 |a computational model
|2 Other
650 _ 7 |a spinal cord
|2 Other
650 _ 7 |a amyotrophic lateral sclerosis
|2 Other
650 _ 7 |a in vivo
|2 Other
650 _ 7 |a electrophysiology
|2 Other
650 _ 7 |a magnetic resonance imaging
|2 Other
650 _ 7 |a mice
|2 Other
700 1 _ |a Wasicki, Bartosz
|0 0009-0008-0521-6851
|b 1
700 1 _ |a Abaei, Alireza
|0 0000-0003-2287-6495
|b 2
700 1 _ |a Scekic-Zahirovic, Jelena
|0 P:(DE-2719)9001282
|b 3
700 1 _ |a roselli, francesco
|0 P:(DE-2719)2812851
|b 4
700 1 _ |a Fernandes, Sofia Rita
|0 0000-0002-0576-8364
|b 5
700 1 _ |a Bączyk, Marcin
|0 0000-0002-2656-9655
|b 6
773 _ _ |a 10.5281/zenodo.15348780
787 0 _ |a de Oliveira Pires, L. et.al.
|d Amsterdam [u.a.] : Elsevier Science, 2025
|i RelatedTo
|0 DZNE-2025-01137
|r
|t A computational model of tsDCS effects in SOD1 mice: from MRI-based design to validation.
909 C O |o oai:pub.dzne.de:281804
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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913 1 _ |a DE-HGF
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|0 G:(DE-HGF)POF4-352
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|v Disease Mechanisms
|x 0
914 1 _ |y 2025
920 1 _ |0 I:(DE-2719)1910001
|k AG Roselli
|l Metabolic Changes in Neurodegeneration
|x 0
980 _ _ |a dataset
980 _ _ |a VDB
980 _ _ |a I:(DE-2719)1910001
980 _ _ |a UNRESTRICTED

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