Journal Article (Review Article)

DZNE-2025-01292

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Management of neuropsychiatric, motor and non-motor symptoms in Parkinson´s disease after long distance air travel: a consensus view.

Poplawska-Domaszewicz, K. ; Kaasinen, V. ; van der Plas, A. A. ; Barbosa, P. M. ; Heim, B. ; Slawek, J. ; Falup-Pecurariu, C. ; Pirtosek, Z. ; Storch, A.DZNE* ; Chen, R. ; Schröter, N. ; Jost, W. H. ; Chaudhuri, K. R.

2025
Springer Wien [u.a.]

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Please use a persistent id in citations: doi:10.1007/s00702-025-02982-4

Abstract: High altitude airline travel can have various effects on health in normal subjects. The effect of airline long distance travelling at high altitude on Parkinson's disease is not clearly known, and occasional reports suggest that after long-haul flights parkinsonian motor and aspects of nonmotor states may worsen temporarily. Worsening of parkinsonian state may be linked to air travel related dehydration, hypoxic effect of decreased oxyhaemoglobin saturation, jet lag, alteration in timing of drug intake as well as potential effect on sleep wake cycle and autonomic dysfunction causing syncope. Although symptoms are generally reversible, appropriate pre-travel planning, personalized to Parkinson's disease subtype and disease, is essential to mitigate risks. Here, we provide an evidence-based overview of challenges and management strategies for Parkinson's disease patients undertaking long-distance air travel.

Keyword(s): Humans (MeSH) ; Parkinson Disease: therapy (MeSH) ; Parkinson Disease: complications (MeSH) ; Parkinson Disease: physiopathology (MeSH) ; Air Travel (MeSH) ; Consensus (MeSH) ; Airline travel ; Dehydration ; Hypoxia ; Nonmotor ; Parkinson’s disease ; Syncope

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Contributing Institute(s):

1. Non-Motor Symptoms in Parkinson's disease (AG Storch)

Research Program(s):

1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

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Database coverage:
; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; DEAL Springer ; DEAL Springer ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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