%0 Journal Article
%A Lohner, Valerie
%A Perna, Laura
%A Schöttker, Ben
%A Perneczky, Robert
%A Kliegel, Matthias
%A Brenner, Hermann
%A Mons, Ute
%T Prospective associations of blood-based biomarkers of neurodegenerative diseases with cognitive performance in a cohort of patients with chronic coronary syndrome.
%J Journal of Alzheimer's disease
%V 108
%N 4
%@ 1387-2877
%C Amsterdam
%I IOS Press
%M DZNE-2025-01361
%P 1507 - 1513
%D 2025
%X In a cohort of persons with chronic coronary syndrome, we investigated associations of blood-based biomarkers of neurodegenerative diseases with cognitive scores and mild cognitive impairment (MCI) after ten years. Biomarker levels were measured in baseline samples of serum (glial fibrillary acid protein, neurofilament light chain (NfL), phosphorylated tau181; n = 363) or plasma (amyloid-β42/40-ratio, total-tau; n = 232). Cognitive scores and MCI were measured at ten-year follow-up using the Cognitive Telephone Screening Instrument. At follow-up, 14.7
%K Humans
%K Male
%K Female
%K Biomarkers: blood
%K Aged
%K Cognitive Dysfunction: blood
%K Cognitive Dysfunction: psychology
%K Neurofilament Proteins: blood
%K Middle Aged
%K Amyloid beta-Peptides: blood
%K tau Proteins: blood
%K Prospective Studies
%K Neurodegenerative Diseases: blood
%K Neurodegenerative Diseases: complications
%K Cohort Studies
%K Peptide Fragments: blood
%K Glial Fibrillary Acidic Protein: blood
%K Neuropsychological Tests
%K Cognition: physiology
%K Alzheimer's disease (Other)
%K amyloid-beta ratio (Other)
%K biomarkers of neurodegenerative diseases (Other)
%K chronic coronary syndrome (Other)
%K cognition (Other)
%K epidemiology (Other)
%K mild cognitive impairment (Other)
%K neurofilament light chain (Other)
%K Biomarkers (NLM Chemicals)
%K Neurofilament Proteins (NLM Chemicals)
%K Amyloid beta-Peptides (NLM Chemicals)
%K tau Proteins (NLM Chemicals)
%K Peptide Fragments (NLM Chemicals)
%K neurofilament protein L (NLM Chemicals)
%K Glial Fibrillary Acidic Protein (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:41252287
%R 10.1177/13872877251389147
%U https://pub.dzne.de/record/282603