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@INPROCEEDINGS{Jeran:283070,
author = {Jeran, Lina Charlotte and Blecha, Nadia and Rodriguez,
Francisca S and Michalowsky, Bernhard and Teipel, Stefan and
Hoffmann, Wolfgang and Thyrian, Jochen René and Blotenberg,
Iris},
title = {{S}ocial {S}upport {P}redicts {D}epressive {S}ymptoms in
{D}ementia – {A} {F}our‐{Y}ear {L}ongitudinal {S}tudy},
journal = {Alzheimer's and dementia},
volume = {21},
number = {Suppl 4},
issn = {1552-5260},
reportid = {DZNE-2025-01477},
pages = {e102810},
year = {2025},
abstract = {Depressive symptoms are a common neuropsychological symptom
in people with dementia. They are associated with reduced
well-being and may exacerbate dementia symptoms. So far,
there has been little research on how modifiable factors,
such as the social environment, are associated with the
severity of symptoms. The aim of the present study was to
investigate the role of support from the social environment
for depressive symptoms in community-dwelling people with
dementia - beyond sociodemographic and clinical factors.We
used data from 378 people screened positive for dementia in
primary care (Mage = 80.2, $59.5\%$ female) who were
interviewed annually in their homes by specially qualified
nurses. Social support was assessed using the Questionnaire
for the Assessment of Social Support (FSozU), depressive
symptoms were measured using the Geriatric Depression Scale
(GDS). We used multilevel growth curve models with random
intercepts and slopes to model depressive symptoms over
time. We modelled both the role of between-person
differences and the role of within-person changes in social
support for depressive symptoms.At the beginning of the
study, the number of people with dementia who reported mild
to severe depressive symptoms was 15.6 $\%.$ More social
support was associated with fewer depressive symptoms
overall over the four-year period (blog = -0.27, $\%$
change: -23.66, $95\%$ CI: -32.29, -13.93). A decline in
social support was associated with more depressive symptoms
(blog = -0.23, $\%$ change: -20.55, $95\%$ CI: -28.82,
-12.19). These effects remained stable after controlling for
sociodemographic and clinical factors.This is the first
study to show that the social environment plays an important
role in depressive symptoms in people with dementia - above
and beyond clinical factors. Social support as a modifiable
factor may be a lever for alleviating depressive symptoms in
dementia. In the care of people with dementia, not only
medical but also psychosocial needs should be given greater
attention.},
month = {Jul},
date = {2025-07-27},
organization = {Alzheimer’s Association
International Conference, Toronto
(Canada), 27 Jul 2025 - 31 Jul 2025},
keywords = {Humans / Dementia: psychology / Dementia: complications /
Female / Male / Social Support / Depression: psychology /
Depression: epidemiology / Aged, 80 and over / Aged /
Surveys and Questionnaires / Psychiatric Status Rating
Scales / Independent Living},
cin = {AG Thyrian / AG Rodriguez / AG Michalowsky / AG Hoffmann},
ddc = {610},
cid = {I:(DE-2719)1510800 / I:(DE-2719)1510900 /
I:(DE-2719)5000067 / I:(DE-2719)1510600},
pnm = {353 - Clinical and Health Care Research (POF4-353)},
pid = {G:(DE-HGF)POF4-353},
typ = {PUB:(DE-HGF)1 / PUB:(DE-HGF)16},
pubmed = {pmid:41448200},
pmc = {pmc:PMC12740431},
doi = {10.1002/alz70858_102810},
url = {https://pub.dzne.de/record/283070},
}