Abstract/Journal Article DZNE-2025-01477

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Social Support Predicts Depressive Symptoms in Dementia – A Four‐Year Longitudinal Study

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2025

Alzheimer’s Association International Conference, AAIC 25, TorontoToronto, Canada, 27 Jul 2025 - 31 Jul 20252025-07-272025-07-31 Alzheimer's and dementia 21(Suppl 4), e102810 () [10.1002/alz70858_102810]

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Abstract: Depressive symptoms are a common neuropsychological symptom in people with dementia. They are associated with reduced well-being and may exacerbate dementia symptoms. So far, there has been little research on how modifiable factors, such as the social environment, are associated with the severity of symptoms. The aim of the present study was to investigate the role of support from the social environment for depressive symptoms in community-dwelling people with dementia - beyond sociodemographic and clinical factors.We used data from 378 people screened positive for dementia in primary care (Mage = 80.2, 59.5% female) who were interviewed annually in their homes by specially qualified nurses. Social support was assessed using the Questionnaire for the Assessment of Social Support (FSozU), depressive symptoms were measured using the Geriatric Depression Scale (GDS). We used multilevel growth curve models with random intercepts and slopes to model depressive symptoms over time. We modelled both the role of between-person differences and the role of within-person changes in social support for depressive symptoms.At the beginning of the study, the number of people with dementia who reported mild to severe depressive symptoms was 15.6 %. More social support was associated with fewer depressive symptoms overall over the four-year period (blog = -0.27, % change: -23.66, 95% CI: -32.29, -13.93). A decline in social support was associated with more depressive symptoms (blog = -0.23, % change: -20.55, 95% CI: -28.82, -12.19). These effects remained stable after controlling for sociodemographic and clinical factors.This is the first study to show that the social environment plays an important role in depressive symptoms in people with dementia - above and beyond clinical factors. Social support as a modifiable factor may be a lever for alleviating depressive symptoms in dementia. In the care of people with dementia, not only medical but also psychosocial needs should be given greater attention.

Keyword(s): Humans (MeSH) ; Dementia: psychology (MeSH) ; Dementia: complications (MeSH) ; Female (MeSH) ; Male (MeSH) ; Social Support (MeSH) ; Depression: psychology (MeSH) ; Depression: epidemiology (MeSH) ; Aged, 80 and over (MeSH) ; Aged (MeSH) ; Surveys and Questionnaires (MeSH) ; Psychiatric Status Rating Scales (MeSH) ; Independent Living (MeSH)

Classification:

Contributing Institute(s):
  1. Interventional Health Care Research (IHCR) (AG Thyrian)
  2. Psychosocial Epidemiology and Public Health (AG Rodriguez)
  3. Patient-Reported Outcomes and Health Economics Research (AG Michalowsky)
  4. Translational Health Care Research (AG Hoffmann)
Research Program(s):
  1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2025
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Medline ; Creative Commons Attribution CC BY 4.0 ; OpenAccess ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; DEAL Wiley ; Essential Science Indicators ; IF >= 10 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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Institute Collections > ROS DZNE > ROS DZNE-AG Michalowsky
Document types > Articles > Journal Article
Institute Collections > ROS DZNE > ROS DZNE-AG Rodriguez
Institute Collections > ROS DZNE > ROS DZNE-AG Hoffmann
Institute Collections > ROS DZNE > ROS DZNE-AG Thyrian
Document types > Presentations > Abstracts
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 Record created 2025-12-29, last modified 2025-12-29


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