TY  - JOUR
AU  - Doludda, Birte
AU  - Barde, Warsha
AU  - D'Egidio, Francesco
AU  - Fitzsimons, Carlos P
AU  - Frisén, Jonas
AU  - Gage, Fred H
AU  - Jessberger, Sebastian
AU  - Lazarov, Orly
AU  - Lie, D Chichung
AU  - Lucassen, Paul J
AU  - de Lucia, Chiara
AU  - Salta, Evgenia
AU  - Song, Hongjun
AU  - Song, Juan
AU  - Thuret, Sandrine
AU  - Toda, Tomohisa
AU  - Kempermann, Gerd
TI  - Adult neurogenesis: New neurons, new opportunities.
JO  - Cell stem cell
VL  - 33
IS  - 3
SN  - 1934-5909
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - DZNE-2026-00246
SP  - 382 - 392
PY  - 2026
AB  - The 38 currently registered clinical trials with the keyword 'adult neurogenesis' indicate growing interest in new neurons as a target for intervention. Today, we have strong evidence that adult neurogenesis is involved in hippocampal function and can contribute to brain functions in health and disease. Neurogenesis research can now ask new questions, such as (1) the identity of stem cells and their input integration for initiating neurogenesis, (2) the nature of the neurogenic niche and neurogenesis without stem cell activity, (3) the complex functionality beyond the hippocampus, and (4) evolutionary and computational theory, including neurogenic neural networks for artificial intelligence.
KW  - Neurogenesis: physiology
KW  - Humans
KW  - Neurons: cytology
KW  - Neurons: physiology
KW  - Animals
KW  - Hippocampus: cytology
KW  - Hippocampus: physiology
KW  - Adult
KW  - Neural Stem Cells: cytology
KW  - hippocampus (Other)
KW  - learning (Other)
KW  - neural networks (Other)
KW  - plasticity (Other)
KW  - stem cells (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41795427
DO  - DOI:10.1016/j.stem.2026.01.014
UR  - https://pub.dzne.de/record/285469
ER  -