AG Schmid München

Genetic Models of Neurodegeneration Also known as:AG Schmid München; ALS, FTLD and Zebrafish models; Fish Core Unit; Genetische Modelle der Neurodegeneration; Zebrafisch Modelle; Zebrafish Models
IDI:(DE-2719)1140002

M DZNE

Recent Publications

All known publications ...
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The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling.
The journal of clinical investigation 134(16), e170550 () [10.1172/JCI170550] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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ALL-R: An Anchoring Score to Predict Relapse in Acute Lymphoblastic Leukemia (ALL) Using a Zebrafish Patient-Derived Xenograft Model
66th American Society of Hematology Annual Meeting, ASH, San DiegoSan Diego, USA, 7 Dec 2024 - 10 Dec 20242024-12-072024-12-10 Blood 144(Supplement 1), 275 () [10.1182/blood-2024-209569]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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In vivo monitoring of leukemia-niche interactions in a zebrafish xenograft model.
PLOS ONE 19(8), e0309415 () [10.1371/journal.pone.0309415] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits.
Molecular neurodegeneration 19(1), 50 () [10.1186/s13024-024-00735-7] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Endothelial TDP-43 controls sprouting angiogenesis and vascular barrier integrity, and its deletion triggers neuroinflammation.
JCI insight 9(5), e177819 () [10.1172/jci.insight.177819] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis.
Molecular metabolism 74, 101748 () [10.1016/j.molmet.2023.101748] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1.
Frontiers in cell and developmental biology 11, 1169962 () [10.3389/fcell.2023.1169962] OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Myelination generates aberrant ultrastructure that is resolved by microglia.
The journal of cell biology 222(3), e202204010 () [10.1083/jcb.202204010] Embargoed OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury.
Nature neuroscience 25(12), 1608 - 1625 () [10.1038/s41593-022-01199-y]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Interaction between VPS13A and the XK scramblase is important for VPS13A function in humans.
Journal of cell science 135(17), jcs260227 () [10.1242/jcs.260227] pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

All known publications ...
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 Record created 2020-02-18, last modified 2024-08-16



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