AG Misgeld
Neuronal Cell Biology
Also known as:AG Misgeld; Neuronale Zellbiologie
⇧ M DZNE ⇧
Recent Publications
All known publications ...
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Journal Article
Heger, L.Extern* ; Kertess, L. ; Kaufhold, C. M.Extern* ; Gubinelli, F.Extern* ; Cardona-Alberich, A. ; Özata, G. ; Müller, S. A.DZNE* ; Tschirner, S. K.DZNE* ; Stehling, O. ; Schifferer, M.DZNE* ; Peron, C. ; Tiranti, V. ; Lill, R. ; Iuso, A. ; Zecca, L. ; Strupp, M. ; Oertel, W. ; Lichtenthaler, S. F.DZNE* ; Burbulla, L. F. (Last author)DZNE*
Patient-Derived Neurons Exhibit α-Synuclein Pathology and Previously Unrecognized Major Histocompatibility Complex Class I Elevation in Mitochondrial Membrane Protein-Associated Neurodegeneration.
Movement disorders 40(12), 2811 - 2818 (2025) [10.1002/mds.70029]2025
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Journal Article
Saller, B. S. ; Wöhrle, S. ; Fischer, L.Extern* ; et al
Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation.
Immunity 58(1), 90 - 107.e11 (2025) [10.1016/j.immuni.2024.10.012]2025
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Journal Article
Simonetti, F. (First author)DZNE* ; Zhong, W. ; Hutten, S. ; Uliana, F. ; Schifferer, M.DZNE* ; Rezaei, A.DZNE* ; Ramirez, L. M.DZNE* ; Hochmair, J.DZNE* ; Sankar, R.DZNE* ; Gopalan, A. ; Kielisch, F. ; Riemenschneider, H.DZNE* ; Ruf, V. ; Schmidt, C. ; Simons, M.DZNE* ; Zweckstetter, M.DZNE* ; Wegmann, S.DZNE* ; Lashley, T. ; Polymenidou, M. ; Edbauer, D.DZNE* ; Dormann, D.
Direct interaction between TDP-43 and Tau promotes their co-condensation, while suppressing Tau fibril formation and seeding.
The EMBO journal 44(24), 7395 - 7433 (2025) [10.1038/s44318-025-00590-2]2025
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Journal Article
Bhattacharya, D.Extern* ; da Silva-Buttkus, P. ; Nalbach, K.DZNE* ; Cheng, L.Extern* ; Garrett, L. ; Irmler, M. ; Kislinger, G.DZNE* ; Werner, G.Extern* ; Rodde, R. ; Lengger, C. ; Beckers, J. ; Zimprich, A. ; Hölter, S. M. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabe de Angelis, M. ; Wefers, B.DZNE* ; Wurst, W.DZNE* ; Brill, M. S. ; Schifferer, M.DZNE* ; Lichtenthaler, S. F.DZNE* ; Behrends, C.
Neuropathy-associated Tecpr2 mutation knock-in mice reveal endolysosomal loss of function phenotypes in neurons and microglia.
Cell death & disease 16(1), 775 (2025) [10.1038/s41419-025-08168-w]2025
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Journal Article
Woo, M. S. ; Brand, J. ; Bal, L. C. ; Moritz, M. ; Walkenhorst, M. ; Vieira, V. ; Ipenberg, I. ; Rothammer, N. ; Wang, M. ; Dogan, B. ; Loreth, D. ; Mayer, C. ; Nagel, D. ; Wagner, I. ; Pfeffer, L. K. ; Landgraf, P. ; van Ham, M. ; Mattern, K. M. ; Winschel, I. ; Frantz, N. ; Sonner, J. K. ; Grosshans, H. K. ; Miguela, A. ; Bauer, S. ; Meurs, N. ; Müller, A. ; Binkle-Ladisch, L. ; Salinas, G. ; Jänsch, L. ; Dieterich, D. C. ; Riedner, M. ; Krüger, E. ; Heppner, F. L.DZNE* ; Glatzel, M. ; Puelles, V. G. ; Engler, J. B. ; Nyengaard, J. R. ; Misgeld, T.DZNE* ; Kerschensteiner, M. ; Merkler, D. ; Meyer-Schwesinger, C. ; Friese, M. A.
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis.
Cell 188(17), 4567 - 4585.e32 (2025) [10.1016/j.cell.2025.05.029]2025
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Journal Article
Gavoci, A. ; Zhiti, A. ; Rusková, M. ; Magiera, M. M. ; Wang, M. ; Ziegler, K. A. ; Hausrat, T. J. ; Ugwuja, A. I. ; Chakraborty, S. ; Engelhardt, S. ; Kneussel, M. ; Balastik, M. ; Janke, C. ; Misgeld, T.DZNE* ; Brill, M. S.
Polyglutamylation of microtubules drives neuronal remodeling.
Nature Communications 16(1), 5384 (2025) [10.1038/s41467-025-60855-6]2025
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Journal Article
Khalin, I. ; Adarsh, N. ; Schifferer, M.DZNE* ; Wehn, A. ; Boide-Trujillo, V. J. ; Mamrak, U. ; Shrouder, J. ; Misgeld, T.DZNE* ; Filser, S. (Last author)DZNE* ; Klymchenko, A. S. ; Plesnila, N.
Nanocarrier Drug Release and Blood-Brain Barrier Penetration at Post-Stroke Microthrombi Monitored by Real-Time Förster Resonance Energy Transfer.
ACS nano 19(15), 14780 - 14794 (2025) [10.1021/acsnano.4c17011]2025
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Journal Article
Dinkel, L. (First author)DZNE* ; Hummel, S.Extern* ; Zenatti, V.DZNE* ; Malara, M.DZNE* ; Tillmann, Y.DZNE* ; Colombo, A. V.DZNE* ; Sebastian Monasor, L.DZNE* ; Suh, J. H. ; Logan, T. ; Roth, S. ; Paeger, L.DZNE* ; Hoffelner, P. ; Bludau, O. ; Schmidt, A.DZNE* ; Müller, S. A.DZNE* ; Schifferer, M.DZNE* ; Nuscher, B. ; Njavro, J. R.DZNE* ; Prestel, M.DZNE* ; Bartos, L. M. ; Wind-Mark, K.DZNE* ; Slemann, L. ; Hoermann, L. ; Kunte, S. T. ; Gnoerich, J.Extern* ; Lindner, S. ; Simons, M.DZNE* ; Herms, J.DZNE* ; Paquet, D. ; Lichtenthaler, S. F.DZNE* ; Bartenstein, P. ; Franzmeier, N. ; Liesz, A. ; Grosche, A. ; Bremova-Ertl, T. ; Catarino, C. ; Beblo, S. ; Bergner, C. ; Schneider, S. A. ; Strupp, M. ; Di Paolo, G. ; Brendel, M.DZNE* ; Tahirovic, S. (Last author)DZNE*
Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
Science translational medicine 16(776), eadl4616 (2024) [10.1126/scitranslmed.adl4616]2024
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Dataset
Schifferer, M.DZNE* ; Rodriguez Martinez, L.Extern* ; Kislinger, G.Extern* ; Fabig, G. ; Wehn, A. ; Jiang, H.Extern* ; Niemann, C.Extern* ; Klymchenko, A. S. ; Plesnila, N. ; Misgeld, T.Extern* ; Müller-Reichert, T. ; Khalin, I.
Dataset: ATUM-Tomo: A multi-scale approach to cellular ultrastructure by combined volume scanning electron microscopy and electron tomography
BioImage Archive (2024) [10.6019/s-biad1274]2024
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Journal Article
Kaji, S.DZNE* ; Berghoff, S. A.DZNE* ; Spieth, L.DZNE* ; Schlaphoff, L.DZNE* ; Sasmita, A. O. ; Vitale, S.DZNE* ; Büschgens, L. ; Kedia, S.DZNE* ; Zirngibl, M.DZNE* ; Nazarenko, T.DZNE* ; Damkou, A.DZNE* ; Hosang, L. ; Depp, C. ; Kamp, F.DZNE* ; Scholz, P. ; Ewers, D. ; Giera, M. ; Ischebeck, T. ; Wurst, W.DZNE* ; Wefers, B.DZNE* ; Schifferer, M.DZNE* ; Willem, M. ; Nave, K.-A. ; Haass, C.DZNE* ; Arzberger, T.Extern* ; Jäkel, S. ; Wirths, O. ; Saher, G. ; Simons, M. (Last author)DZNE*
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Immunity 57(11), 2651 - 2668.e12 (2024) [10.1016/j.immuni.2024.09.014]2024
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All known publications ...
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