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AG Kahle
Functional Neurogenetics Also known as:AG Kahle; Funktionelle Neurogenetik; Neurodegeneration; Parkinson's Disease GeneticsID | I:(DE-2719)1210000-4 |
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Journal Article
Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors.
Genome biology 25(1), 301 (2024) [10.1186/s13059-024-03438-w]
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Reduction of brain stem pathology and transient amelioration of early cognitive symptoms in transgenic mice treated with a monoclonal antibody against α-synuclein oligomers/protofibrils.
Aging brain 4, 100086 (2023) [10.1016/j.nbas.2023.100086]
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Failure of diet-induced transcriptional adaptations in alpha-synuclein transgenic mice.
Human molecular genetics 32(3), 450 - 461 (2023) [10.1093/hmg/ddac205]
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Signatures of glial activity can be detected in the CSF proteome
Proceedings of the National Academy of Sciences of the United States of America 119(24), e2119804119 (2022) [10.1073/pnas.2119804119]
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Temporal Analysis of Protein Ubiquitylation and Phosphorylation During Parkin-Dependent Mitophagy.
Molecular & cellular proteomics 21(2), 100191 (2022) [10.1016/j.mcpro.2021.100191]
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Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.
Nature Communications 13(1), 1223 (2022) [10.1038/s41467-022-28822-7]
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Parkin-dependent mitophagy occurs via proteasome-dependent steps sequentially targeting separate mitochondrial sub-compartments for autophagy
Autophagy reports 1(1), 576 - 602 (2022) [10.1080/27694127.2022.2143214]
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Journal Article (Review Article)
Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications.
The journal of biological chemistry 297(5), 101339 (2021) [10.1016/j.jbc.2021.101339]
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LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.
EMBO molecular medicine 13(9), e14745 (2021) [10.15252/emmm.202114745]
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Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures.
Molecular neurodegeneration 16(1), 54 (2021) [10.1186/s13024-021-00471-2]
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