Journal Article

DZNE-2020-05672

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png The Impact of Lens Opacity on SD-OCT Retinal Nerve Fiber Layer and Bruch's Membrane Opening Measurements Using the Anatomical Positioning System (APS).

Mauschitz, M. M. (First author)DZNE* ; Roth, F. ; Holz, F. G. ; Breteler, M. M. B.DZNE* ; Finger, R. P. (Corresponding author)

2017
ARVO Rockville, Md.

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Please use a persistent id in citations: doi:10.1167/iovs.17-21675

Abstract: To evaluate the impact of lens opacity on retinal nerve fiber layer thickness (RNFLT) and Bruch's membrane opening (BMO) measurements.Fifty-nine randomly selected patients without any other relevant ocular pathology undergoing elective routine cataract surgery in two specialized eye clinics were enrolled. RNFLT, BMO area, and BMO minimum rim width (BMO-MRW) were assessed with the Heidelberg Engineering Spectralis OCT using the anatomical positioning system (APS) prior to and 1 day after cataract surgery using a ring scan at different eccentricities of the disc (3.5, 4.1 and 4.7 mm). Lens opacity was quantified using densitometry based on Scheimpflug images (Oculus Pentacam AXL).RNFLT, BMO area, and BMO-MRW were virtually identical before and following removal of the cataractous lens. This held when assessed overall, within the six sectors for the 3.5-mm scan, or at any other eccentricity. Baseline RNFLT was not associated with lens opacity.Using the APS, RNFLT remained unchanged following cataract surgery, contrary to results reported by previous studies. Our results imply that the APS may have contributed to more precise spectral-domain optical coherence measurements, minimizing the influence of cataract on RNFLT and BMO assessments in our cohort.

Keyword(s): Aged (MeSH) ; Bruch Membrane: anatomy & histology (MeSH) ; Cataract: complications (MeSH) ; Densitometry (MeSH) ; Female (MeSH) ; Humans (MeSH) ; Lens Implantation, Intraocular (MeSH) ; Male (MeSH) ; Nerve Fibers (MeSH) ; Phacoemulsification (MeSH) ; Postoperative Period (MeSH) ; Preoperative Period (MeSH) ; Retinal Ganglion Cells: cytology (MeSH) ; Tomography, Optical Coherence: methods (MeSH)

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Contributing Institute(s):

1. Population Health Sciences (AG Breteler 1)

Research Program(s):

1. 345 - Population Studies and Genetics (POF3-345) (POF3-345)

Appears in the scientific report 2017

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Database coverage:
; ; ; ; BIOSIS Previews ; BIOSIS Reviews Reports And Meetings ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; DOAJ Seal ; IF < 5 ; JCR ; SCOPUS ; Web of Science Core Collection

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Linked articles:

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Erratum/Correction) Mauschitz, M. (First author)DZNE* ; Breteler, M.DZNE*
Erratum in: “The Impact of Lens Opacity on SD-OCT Retinal Nerve Fiber Layer and Bruch's Membrane Opening Measurements Using the Anatomical Positioning System (APS)” by Matthias M. Mauschitz, Felix Roth, Frank G. Holz, Monique M. B. Breteler, and Robert P. Finger (Invest Ophthalmol Vis Sci. 2017;58:2804–2809) doi:10.1167/iovs.17-21675
Investigative ophthalmology & visual science 58(10), 4248 (2017) [10.1167/iovs.17-21675a]2017   Files BibTeX | EndNote: XML, Text | RIS

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