Journal Article

DZNE-2020-01066

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dystonia Non-Motor Symptoms Questionnaire (DNMSQuest) zur Erhebung nichtmotorischer Symptome bei Dystonie | Dystonia Non-Motor Symptoms Questionnaire (DNMSQuest) for assessment of non-motor symptoms in dystonia

Klingelhoefer, L. ; Jost, W. ; Odin, P. ; Storch, A.DZNE* ; Ray Chaudhuri, K. ; Reichmann, H.

2020
Springer Heidelberg

This record in other databases:  

Please use a persistent id in citations: doi:10.1007/s00115-020-00885-1

Abstract: BackgroundNon-motor symptoms (NMS) in patients with dystonia have a relevant impact on health-related quality of life; however, a comprehensive easy to use NMS assessment tool for clinical bedside use is currently not available.ObjectiveThe validated German version of the dystonia non-motor symptoms questionnaire (DNMSQuest) for assessing NMS in craniocervical dystonia is presented.MethodsThe DNMSQuest in the German language was developed based on internationally recognized standards for intercultural adaptation of self-completed patient questionnaires. Translation of the original English questionnaire into the German language as well as back translation to English was carried out independently by four bilingual specialists in neurological movement disorders. In each case a consensus version accepted by each translator was created by another neurologist. The back translated English version was compared with the original English questionnaire for relevant linguistic and content discrepancies by a neurologist who was significantly involved in the development of the original questionnaire. The final German version was used in 130 patients with cervical dystonia and 48 healthy controls in an international, multicenter validation study.ResultsAn interculturally adapted validated version of the DNMSQuest in the German and English languages was developed for rapid bedside assessment and evaluation of NMS in cervical dystonia.ConclusionThe DNMSQuest successfully bridges the current gap of a validated disease-specific, patient self-administered, short, comprehensive questionnaire for NMS assessment in routine clinical practice in craniocervical dystonia. It is envisaged that this tool will be useful for the clinical practice and trials.Die Kenntnis nichtmotorischer Symptome bei Patienten mit Dystonie, deren Erhebung und Behandlung im klinischen Alltag sind wichtig, da diese neben den motorischen Beschwerden einen relevanten Einfluss auf die Lebensqualität haben. Der Dystonia Non-Motor Symptoms Questionnaire als einfacher und schnell durch die Patienten selbst auszufüllender Fragebogen erfasst 7 verschiedene Domänen (Schlaf, autonome Symptome, Fatigue, emotionales Wohlbefinden, Stigma, Aktivitäten des täglichen Lebens, sensorische Symptome) und kann zum Erreichen eines ganzheitlichen und erfolgreichen Behandlungskonzeptes bei Patienten mit Dystonie beitragen.

---

Contributing Institute(s):

1. Non-Motor Symptoms in Parkinson's disease (AG Storch 2 Rostock)

Research Program(s):

1. 344 - Clinical and Health Care Research (POF3-344) (POF3-344)

Appears in the scientific report 2020

---

Database coverage:
; ; ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; DEAL Springer ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; SCOPUS ; Web of Science Core Collection

---