Journal Article DZNE-2021-00581

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Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe.

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2022
Wiley Hoboken, NJ

Alzheimer's and dementia 18(1), 29-42 () [10.1002/alz.12365]

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Abstract: Harmonized neuropsychological assessment for neurocognitive disorders, an international priority for valid and reliable diagnostic procedures, has been achieved only in specific countries or research contexts.To harmonize the assessment of mild cognitive impairment in Europe, a workshop (Geneva, May 2018) convened stakeholders, methodologists, academic, and non-academic clinicians and experts from European, US, and Australian harmonization initiatives.With formal presentations and thematic working-groups we defined a standard battery consistent with the U.S. Uniform DataSet, version 3, and homogeneous methodology to obtain consistent normative data across tests and languages. Adaptations consist of including two tests specific to typical Alzheimer's disease and behavioral variant frontotemporal dementia. The methodology for harmonized normative data includes consensus definition of cognitively normal controls, classification of confounding factors (age, sex, and education), and calculation of minimum sample sizes.This expert consensus allows harmonizing the diagnosis of neurocognitive disorders across European countries and possibly beyond.

Keyword(s): Age Factors (MeSH) ; Cognition (MeSH) ; Cognitive Dysfunction: classification (MeSH) ; Cognitive Dysfunction: diagnosis (MeSH) ; Consensus Development Conferences as Topic (MeSH) ; Datasets as Topic: standards (MeSH) ; Educational Status (MeSH) ; Europe (MeSH) ; Expert Testimony (MeSH) ; Humans (MeSH) ; Language (MeSH) ; Neuropsychological Tests: standards (MeSH) ; Sex Factors (MeSH) ; Alzheimer's disease ; cognitive assessment ; diagnosis ; mild cognitive impairment ; mild neurocognitive disorders ; standard neuropsychological assessment

Classification:

Contributing Institute(s):
  1. Coordinator of Clinical Research (AG Endres)
  2. Clinical Dementia Research Rostock /Greifswald (AG Teipel)
  3. Neuropsychology (AG Wagner)
  4. Late-Translational Dementia Research (AG Boccardi)
Research Program(s):
  1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2022
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Medline ; Creative Commons Attribution-NonCommercial CC BY-NC 4.0 ; OpenAccess ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; DEAL Wiley ; Essential Science Indicators ; IF >= 15 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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Document types > Articles > Journal Article
Institute Collections > ROS DZNE > ROS DZNE-AG Boccardi
Institute Collections > ROS DZNE > ROS DZNE-AG Teipel
Institute Collections > BN DZNE > BN DZNE-AG Wagner
Institute Collections > B DZNE > B DZNE-AG Endres
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 Record created 2021-07-19, last modified 2024-03-20


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