Journal Article

DZNE-2022-00802

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Design and Generation of Gene-Targeting Vectors.

Wefers, B.Extern* ; Wurst, W.DZNE* ; Kühn, R.

2011
Wiley Chichester

This record in other databases:    

Please use a persistent id in citations: doi:10.1002/9780470942390.mo100179

Abstract: This unit provides an overview of the major types of mutant alleles that can be generated by gene targeting in ES cells. It presents the growing public resources of premade gene targeting vectors, modified ES cells, and mutant mice. General guidelines for the design of targeting vectors are followed by protocols for the construction of vectors to generate knockout (KO), conditional KO, and subtle mutant alleles. Curr. Protoc. Mouse Biol. 1:199-211. © 2011 by John Wiley & Sons, Inc.

Keyword(s): EUCOMM/KOMP ; conditional KO mice ; gene targeting ; knockout mice ; targeting vector design

---

Contributing Institute(s):

1. Genome Engineering (AG Wurst)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)

Appears in the scientific report 2011

---

Database coverage:
; DEAL Wiley ; SCOPUS

---