AG Zhou
Adaptive Immunity in Neurodegeneration
Also known as:AG Zhou; Adaptive Immunität bei Neurodegeneration
⇧ M DZNE ⇧
Recent Publications
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Journal Article
Rezaei, A. (First author)DZNE* ; Kocsis-Jutka, V. (First author)DZNE* ; Günes, Z. I. ; Zeng, Q. (First author)DZNE* ; Kislinger, G.DZNE* ; Bauernschmitt, F. ; Isilgan, H. B.DZNE* ; Parisi, L. R. ; Kaya, T.DZNE* ; Franzenburg, S. ; Koppenbrink, J.DZNE* ; Knogler, J.DZNE* ; Arzberger, T.Extern* ; Farny, D.DZNE* ; Nuscher, B. ; Katona, E.DZNE* ; Dhingra, A.DZNE* ; Yang, C.DZNE* ; Gouna, G.DZNE* ; LaClair, K.DZNE* ; Janjic, A. ; Enard, W. ; Zhou, Q.DZNE* ; Hagan, N. ; Ofengeim, D. ; Beltrán, E. ; Gökce, O.Extern* ; Simons, M.DZNE* ; Liebscher, S. ; Edbauer, D. (Last author)DZNE*
Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.
Nature Communications 16(1), 3442 (2025) [10.1038/s41467-025-58634-4]2025
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Hausmann, F. ; Caldi Gomes, L. ; Hänzelmann, S. ; Khatri, R. ; Oller, S. ; Gebelin, M. ; Parvaz, M. ; Tzeplaeff, L. ; Pasetto, L. ; Zhou, Q.DZNE* ; Zelina, P. ; Edbauer, D.DZNE* ; Pasterkamp, R. J. ; Rehrauer, H. ; Schlapbach, R. ; Carapito, C. ; Bonetto, V. ; Bonn, S. ; Lingor, P. (Last author)DZNE*
A dataset profiling the multiomic landscape of the prefrontal cortex in amyotrophic lateral sclerosis.
GigaScience 13, giae100 (2024) [10.1093/gigascience/giae100]2024
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de Calbiac, H. ; Renault, S. ; Haouy, G. ; Jung, V. ; Roger, K. ; Zhou, Q.DZNE* ; Campanari, M.-L. ; Chentout, L. ; Demy, D. L. ; Marian, A. ; Goudin, N. ; Edbauer, D.DZNE* ; Guerrera, C. ; Ciura, S. ; Kabashi, E.
Poly-GP accumulation due to C9orf72 loss of function induces motor neuron apoptosis through autophagy and mitophagy defects.
Autophagy 20(10), 2164 - 2185 (2024) [10.1080/15548627.2024.2358736]2024
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Caldi Gomes, L. ; Hänzelmann, S. ; Hausmann, F. ; Khatri, R. ; Oller, S. ; Parvaz, M. ; Tzeplaeff, L. ; Pasetto, L. ; Gebelin, M. ; Ebbing, M. ; Holzapfel, C. ; Columbro, S. F. ; Scozzari, S. ; Knöferle, J. ; Cordts, I. ; Demleitner, A. F. ; Deschauer, M. ; Dufke, C. ; Sturm, M. ; Zhou, Q.DZNE* ; Zelina, P. ; Sudria-Lopez, E. ; Haack, T. B. ; Streb, S. ; Kuzma-Kozakiewicz, M. ; Edbauer, D.DZNE* ; Pasterkamp, R. J. ; Laczko, E. ; Rehrauer, H. ; Schlapbach, R. ; Carapito, C. ; Bonetto, V. ; Bonn, S.Extern* ; Lingor, P. (Last author)DZNE*
Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target.
Nature Communications 15(1), 4893 (2024) [10.1038/s41467-024-49196-y]2024
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Shojaei, M. ; Zhou, Q.DZNE* ; Palumbo, G. ; Schaefer, R. ; Kaskinoro, J. ; Vehmaan-Kreula, P. ; Bartenstein, P. ; Brendel, M.DZNE* ; Edbauer, D.DZNE* ; Lindner, S.
Development and Preclinical Evaluation of a Copper-64-Labeled Antibody Targeting Glycine-Alanine Dipeptides for PET Imaging of C9orf72-Associated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia
ACS pharmacology & translational science 7(5), 1404 - 1414 (2024) [10.1021/acsptsci.4c00037]2024
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Riemenschneider, H. (First author)DZNE* ; Simonetti, F. (First author)DZNE* ; Sheth, U. ; Katona, E. (First author)DZNE* ; Roth, S. ; Hutten, S. ; Farny, D.DZNE* ; Michaelsen, M.DZNE* ; Nuscher, B. ; Schmidt, M. K. ; Flatley, A. ; Schepers, A. ; Gruijs da Silva, L. A. ; Zhou, Q.DZNE* ; Klopstock, T.DZNE* ; Liesz, A. ; Arzberger, T.DZNE* ; Herms, J.DZNE* ; Feederle, R.DZNE* ; Gendron, T. F. ; Dormann, D. ; Edbauer, D. (Last author)DZNE*
Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
Acta Neuropathologica Communications 11(1), 112 (2023) [10.1186/s40478-023-01592-z]2023
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Czuppa, M. (First author)DZNE* ; Dhingra, A.DZNE* ; Zhou, Q.DZNE* ; Schludi, C.DZNE* ; Koenig, L.DZNE* ; Scharf, E.DZNE* ; Farny, D.DZNE* ; Dalmia, A.DZNE* ; Täger, J.DZNE* ; Castillo Lizardo, M. G.DZNE* ; Katona, E.DZNE* ; Mori, K. ; Aumer, T. ; Schelter, F. ; Müller, M. ; Carell, T. ; Kalliokoski, T. ; Messinger, J. ; Rizzu, P.DZNE* ; Heutink, P.DZNE* ; Edbauer, D. (Last author)DZNE*
Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD
Cell reports 39(10), 110913 (2022) [10.1016/j.celrep.2022.110913]2022
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Wagner, M. ; Lorenz, G. ; Volk, A. E. ; Brunet, T. ; Edbauer, D.DZNE* ; Berutti, R. ; Zhao, C. ; Anderl-Straub, S. ; Bertram, L. ; Danek, A.Extern* ; Deschauer, M. ; Dill, V. ; Fassbender, K. ; Fliessbach, K.DZNE* ; Götze, K. S. ; Jahn, H. ; Kornhuber, J. ; Landwehrmeyer, B. ; Lauer, M. ; Obrig, H. ; Prudlo, J.DZNE* ; Schneider, A.DZNE* ; Schroeter, M. L. ; Uttner, I. ; Vukovich, R. C.Extern* ; Wiltfang, J.DZNE* ; Winkler, A. S. ; Zhou, Q.DZNE* ; Ludolph, A. C.DZNE* ; consortium, G. F. (Collaboration Author) ; Oexle, K. ; Otto, M. ; Diehl-Schmid, J.Extern* ; Winkelmann, J. (Corresponding author)
Clinico-genetic findings in 509 frontotemporal dementia patients.
Molecular psychiatry 26(10), 5824-5832 (2021) [10.1038/s41380-021-01271-2]2021
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Heindl, S. ; Ricci, A. ; Carofiglio, O. ; Zhou, Q.DZNE* ; Arzberger, T.Extern* ; Lenart, N. ; Franzmeier, N. ; Hortobagyi, T. ; Nelson, P. T. ; Stowe, A. M. ; Denes, A. ; Edbauer, D.DZNE* ; Liesz, A.
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
Journal of experimental medicine 218(8), e20202411 (2021) [10.1084/jem.20202411]2021
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LaClair, K. D. (First author)DZNE* ; Zhou, Q.DZNE* ; Michaelsen, M.DZNE* ; Wefers, B.DZNE* ; Brill, M. S.DZNE* ; Janjic, A. ; Rathkolb, B. ; Farny, D.DZNE* ; Cygan, M.DZNE* ; de Angelis, M. H. ; Wurst, W.DZNE* ; Neumann, M.DZNE* ; Enard, W. ; Misgeld, T.DZNE* ; Arzberger, T.DZNE* ; Edbauer, D. (Last author)DZNE*
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
Acta neuropathologica 140(2), 121 - 142 (2020) [10.1007/s00401-020-02176-0]2020
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All known publications ...
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