AG Zhou

Adaptive Immunity in Neurodegeneration Also known as:AG Zhou; Adaptive Immunität bei Neurodegeneration
IDI:(DE-2719)5000080

M DZNE

Recent Publications

All known publications ...
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Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.
Nature Communications 16(1), 3442 () [10.1038/s41467-025-58634-4] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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A dataset profiling the multiomic landscape of the prefrontal cortex in amyotrophic lateral sclerosis.
GigaScience 13, giae100 () [10.1093/gigascience/giae100] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Poly-GP accumulation due to C9orf72 loss of function induces motor neuron apoptosis through autophagy and mitophagy defects.
Autophagy 20(10), 2164 - 2185 () [10.1080/15548627.2024.2358736] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target.
Nature Communications 15(1), 4893 () [10.1038/s41467-024-49196-y] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Development and Preclinical Evaluation of a Copper-64-Labeled Antibody Targeting Glycine-Alanine Dipeptides for PET Imaging of C9orf72-Associated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia
ACS pharmacology & translational science 7(5), 1404 - 1414 () [10.1021/acsptsci.4c00037] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
Acta Neuropathologica Communications 11(1), 112 () [10.1186/s40478-023-01592-z] OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD
Cell reports 39(10), 110913 () [10.1016/j.celrep.2022.110913] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Clinico-genetic findings in 509 frontotemporal dementia patients.
Molecular psychiatry 26(10), 5824-5832 () [10.1038/s41380-021-01271-2] OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
Journal of experimental medicine 218(8), e20202411 () [10.1084/jem.20202411] pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
Acta neuropathologica 140(2), 121 - 142 () [10.1007/s00401-020-02176-0] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

All known publications ...
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 Record created 2022-08-10, last modified 2024-09-06



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