Journal Article (Editorial)

DZNE-2025-00853

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Preface to the Special Issue 'History, Biology and Pathobiology of Prions: A Field of Renewed Hopes'.

Outeiro, T. F. (First author)DZNE* ; Vieira, T. C. R. G.

2025
Wiley-Blackwell Oxford

This record in other databases:    

Please use a persistent id in citations: doi:10.1111/jnc.70156

Abstract: Research in the field of prion diseases has not only shed light on the mechanisms underlying transmissible spongiform encephalopathies (TSEs) but has also influenced the broader understanding of protein misfolding disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), and other tauopathies and synucleinopathies. Although prion diseases are rare and invariably fatal, they have provided an invaluable conceptual framework for the study of age-associated neurodegenerative disorders. On the occasion of the 'Prion 2023' meeting in Faro, Portugal, which brought together leading experts in prion biology and neurodegeneration to discuss emerging data and evolving concepts, we put together a special issue on the topic to discuss new structural insights, diagnostic technologies, and the increasing recognition of prion-like mechanisms in a wide range of proteinopathies. This Special Issue features six comprehensive review articles that highlight key advances and ongoing challenges in the study of prions and related disorders.

Keyword(s): Humans (MeSH) ; Prion Diseases: pathology (MeSH) ; Prion Diseases: metabolism (MeSH) ; Prion Diseases: genetics (MeSH) ; Prions: metabolism (MeSH) ; Animals (MeSH) ; alpha‐synuclein ; amyloid ; beta‐amyloid ; cancer ; neurodegeneration ; p53 ; prion ; prion diseases ; protein aggregation ; Prions

---

Contributing Institute(s):

1. Epigenetics and Systems Medicine in Neurodegenerative Diseases (AG Fischer)

Research Program(s):

1. 352 - Disease Mechanisms (POF4-352) (POF4-352)

Appears in the scientific report 2025

---

Database coverage:
; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; DEAL Wiley ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---