Contribution to a book

DZNE-2025-01017

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Functional and Molecular Neuroimaging

Herholz, K. ; Teipel, S.DZNE* ; Hellwig, S. ; Langner, S. ; Rijntjes, M. ; Klöppel, S. ; Weiller, C. ; Meyer, P. T.

2021
Elsevier

Abstract: This chapter provides an overview on the diagnostic utility of positron emission tomography (PET), single-photon emission computed tomography (SPECT), and functional magnetic resonance imaging (fMRI) in neurology. PET is now providing essential imaging biomarkers for Alzheimer disease (AD), especially for its early detection and differentiation from other neurodegenerative diseases such as frontotemporal dementia (FTD) and dementia with Lewy bodies (DLB). PET and SPECT also play important roles for the diagnosis of Parkinson disease, focal epilepsy, paraneoplastic encephalitis, and coma. PET can demonstrate metabolic activity of brain tumors and contribute to therapy planning and early detection of recurrent tumors. Increasingly, fMRI, which is still primarily a tool for research, may also support diagnosis of neurodegenerative diseases, focal epilepsy, and recovery after ischemic stroke. fMRI is also used for the presurgical localization of motor and language function.

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Contributing Institute(s):

1. Clinical Dementia Research (Rostock /Greifswald) (AG Teipel)

Research Program(s):

1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

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