Journal Article (Letter)

DZNE-2025-01300

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Probabilistic Mapping of Magnetic Resonance‐Guided Focused Ultrasound ( MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor‐Dominant Parkinson's Disease: Insights from a German Cohort

Krauss, J. ; Upadhyay, N.Extern* ; Purrer, V.DZNE* ; Borger, V. ; Daamen, M.Extern* ; Weiland, H. ; Schmitt, A.Extern* ; Schmeel, C. ; Radbruch, A.DZNE* ; Essler, M. ; Wüllner, U.DZNE* ; Boecker, H. (Last author)DZNE*

2025
Wiley New York, NY

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Please use a persistent id in citations: doi:10.1002/mds.70003

Abstract: Precise targeting in magnetic resonance-guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor-dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = -12.4, y = -17.5, z = -1.7 (ET) and x = -13.4, y = -19.8, z = -3.0 (TDPD).

Keyword(s): Humans (MeSH) ; Essential Tremor: surgery (MeSH) ; Essential Tremor: diagnostic imaging (MeSH) ; Parkinson Disease: surgery (MeSH) ; Parkinson Disease: diagnostic imaging (MeSH) ; Male (MeSH) ; Female (MeSH) ; Magnetic Resonance Imaging: methods (MeSH) ; Aged (MeSH) ; Thalamus: surgery (MeSH) ; Thalamus: diagnostic imaging (MeSH) ; Middle Aged (MeSH) ; Cohort Studies (MeSH) ; Germany (MeSH) ; Tremor: surgery (MeSH)

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Contributing Institute(s):

1. Positron Emissions Tomography (PET) (AG Boecker)
2. Clinical Research Coordination (Clinical Research (Bonn))
3. Clinical Neuroimaging (AG Radbruch)
4. Biomarker Parkinson's Disease (AG Wüllner)

Research Program(s):

1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2025

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Database coverage:
; ; ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; DEAL Wiley ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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