Dataset

DZNE-2025-01397

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dataset: Parkinson's Disease Mouse Model Brain LC-MS/MS

Lee, J.DZNE* ; Danzer, K. M.DZNE*

2025
PRoteomics IDEntifications Database

Abstract: Brains of a transgenic Parkinson's Disease Mouse Model were used to investigate proteomics using LC-MS/MS. The Model has the human alpha-synuclein expression under the Control of CamkIIa promotor and a DOX system, making the expression inducible. Data includes aging, long expression, short expression, no expression as conditions

---

Contributing Institute(s):

1. Mechanisms of Propagation (AG Danzer)

Research Program(s):

1. 352 - Disease Mechanisms (POF4-352) (POF4-352)

Appears in the scientific report 2025

---

---

Linked articles:

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Bopp, V.Extern* ; Lee, J. (First author)DZNE* ; Oeckl, P.DZNE* ; Kühlwein, J.Extern* ; Grozdanov, V.Extern* ; Kiechle, M. ; Mayer, B. ; Möhrle, B. ; Geiger, H. ; Danzer, K. M. (Last author)DZNE*
Targeting Cdc42 improves motor phenotype in Parkinson’s disease mice and reveals age-dependent susceptibility to α-synuclein
iScience 28(12), 114217 (2025) [10.1016/j.isci.2025.114217]2025   Files BibTeX | EndNote: XML, Text | RIS

---