Journal Article

DZNE-2026-00299

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Feasibility and effects of an online multimodal mind–body intervention on mental and physical well‐being in older adults: The REMIND er randomized controlled study

Stamer, S. (First author)DZNE* ; Lipska-Dieck, A.DZNE* ; Luft, M.DZNE* ; Reif, K. P.DZNE* ; Koch, S. C. ; Mauer, R. ; Klimecki-Lenz, O. M.Extern* ; Wirth, M. (Last author)DZNE*

2026
Wiley [Hoboken, NJ]

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Please use a persistent id in citations: doi:10.1002/bsa3.70071

Abstract: INTRODUCTION: Aging populations require scalable, accessible, and inclusive lifestyle interventions that address multiple modifiable dementia risk factors.METHODS: The REMINDer pilot randomized controlled trial, randomized (1:1) healthy older adults (≥ 60 years, retired) to a 6-week online multimodal mind–body group intervention or a delayed-intervention control group. The live-streamed, home-based, two 1-hour sessions/week program integrates music, dance movement, and mindfulness via video conferencing. Primary outcomes were feasibility (adherence benchmark: ≥ 60%) and changes in mental and physical well-being (Health-Survey SF-12). Secondary outcomes comprised feasibility metrics and safety.RESULTS: Intention-to-treat analyses included 68 participants (mean [standard deviaton {SD}] age: 69.2 [5.2] years; 80.9% women). Mean (SD) adherence was 80% (30%), exceeding the predefined benchmark (p = 0.010). There were no group differences in SF-12 mental (p = 0.827) or physical well-being (p = 0.656) from pre-to-post intervention. Feasibility was high, with 95% reach, 90% retention, and 9% dropout. No serious adverse events occurred.DISCUSSION: The scalable, accessible online multimodal intervention is feasible and safe for older adults.

Note: ClinicalTrials.gov (Identifier: NCT06530277) on July 27, 2024. https://clinicaltrials.gov/study/NCT06530277.DZNE Stiftung – Forschung für ein Leben ohneDemenz, Parkinson und ALS, Grant/AwardNumbers: T0531/36311/2020/kg,T0531/41814/2002/kg

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Contributing Institute(s):

1. Brain Resilience (AG Wirth)

Research Program(s):

1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2026

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Database coverage:
; ; ; DEAL Wiley

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