| Home > In process > Identifying maximal beta power from directional subthalamic local field potentials in Parkinson's disease. |
| Journal Article | DZNE-2026-00495 |
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2026
Springer Nature
[London]
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Please use a persistent id in citations: doi:10.1038/s41531-026-01380-1
Abstract: Accurate subthalamic beta activity could guide deep brain stimulation programming in Parkinson's disease, but bipolar recordings complicate contact selection. In 39 patients, we validated three methods to estimate pseudo-monopolar beta power. Distance-weighted methods (Euclidean, Strelow) agreed consistently with the externalized 'ground-truth' beta distribution. Maximal beta power across 20s windows was more stable in ring than in directional channels. Beta-contacts from all methods aligned with clinically active stimulation contacts one year after surgery.
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