Journal Article DZNE-2026-00495

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Identifying maximal beta power from directional subthalamic local field potentials in Parkinson's disease.

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2026
Springer Nature [London]

npj Parkinson's Disease 12(1), 114 () [10.1038/s41531-026-01380-1]

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Abstract: Accurate subthalamic beta activity could guide deep brain stimulation programming in Parkinson's disease, but bipolar recordings complicate contact selection. In 39 patients, we validated three methods to estimate pseudo-monopolar beta power. Distance-weighted methods (Euclidean, Strelow) agreed consistently with the externalized 'ground-truth' beta distribution. Maximal beta power across 20s windows was more stable in ring than in directional channels. Beta-contacts from all methods aligned with clinically active stimulation contacts one year after surgery.

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Contributing Institute(s):
  1. Movement Disorders (Parkinson's disease, Dystonia) (AG Kühn)
Research Program(s):
  1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Database coverage:
Medline ; Creative Commons Attribution CC BY (No Version) ; DOAJ ; Article Processing Charges ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; DOAJ Seal ; Essential Science Indicators ; Fees ; IF >= 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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Document types > Articles > Journal Article
Institute Collections > B DZNE > B DZNE-AG Kühn
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 Record created 2026-05-11, last modified 2026-05-11


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