Journal Article (Review Article)

DZNE-2026-00660

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Emerging directions in tauopathy research.

Buée, L. ; Wildsmith, K. R. ; Alladi, S. ; Bertucci, T. ; Boche, D. ; Bowles, K. R. ; Boxer, A. ; Brummet, J. ; DeVos, S. L. ; Diaz, K. ; Dreyer, A. J. ; Duff, K. ; Duran-Aniotz, C. ; Durrant, C. S. ; Farrell, K. ; Fontana, I. C. ; Franzmeier, N. ; Frost, B. ; Horie, K. ; Kaňovský, P. ; Kao, A. W. ; Mahinrad, S. ; Malpetti, M. ; Morris, H. R. ; Palleis, C.DZNE* ; Petrucelli, L. ; Rexach, J. ; Reyderman, L. ; Rommel, A. ; Rowe, J. B. ; Sanabria Bohórquez, S. M. ; Sato, C. ; Schöll, M. ; Schneider, A.DZNE* ; de Silva, R. ; Snyder, H. M. ; VandeVrede, L. ; Varga, A. W. ; Vogel, J. W. ; Yeh, F. L. ; Yoo, A. S. ; Carrillo, M. C.

2026
Wiley Hoboken, NJ

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Please use a persistent id in citations: doi:10.1002/alz.71431

Abstract: The Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of tau regulation, degradation, and propagation; advances in biomarker development for the diagnosis and staging of tauopathies; and evolving therapeutic strategies targeting diverse aspects of tau pathophysiology. Discussions also emphasized the importance of cross-sector collaboration, and global initiatives to address disparities in tau research. This report synthesizes key insights from the conference and underscores the critical role of interdisciplinary, biomarker-driven, and globally inclusive approaches in accelerating the translation of tau research into effective clinical applications.

Keyword(s): biomarkers ; neurodegeneration ; precision medicine ; tauopathies ; therapeutics

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Contributing Institute(s):

1. Clinical Research (Munich) (Clinical Research (Munich))
2. Translational Dementia Research (Bonn) (AG Schneider)

Research Program(s):

1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

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Database coverage:
; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; DEAL Wiley ; Essential Science Indicators ; IF >= 10 ; JCR ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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