Journal Article (Editorial) DZNE-2026-00875

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'Heart-in-the-dish' models identify mechanisms of diastolic dysfunction.

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2026
Elsevier Amsterdam [u.a.]

Cell stem cell 33(8), 1243 - 1245 () [10.1016/j.stem.2026.07.007]

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Abstract: Modeling of cardiac pathologies in tissue-engineered models is coming of age. Two independent studies by Reid et al.1 and Tani et al.2 present in-depth multi-phenomics data from a human cardiac organoid (hCO) model and explore hCOs and engineered heart tissues (EHTs) for modeling of diastolic dysfunction.

Keyword(s): Humans (MeSH) ; Diastole (MeSH) ; Tissue Engineering: methods (MeSH) ; Animals (MeSH) ; Heart: physiopathology (MeSH)

Classification:

Contributing Institute(s):
  1. Epigenetics and Systems Medicine in Neurodegenerative Diseases (AG Fischer)
Research Program(s):
  1. 352 - Disease Mechanisms (POF4-352) (POF4-352)

Database coverage:
Medline ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Essential Science Indicators ; IF >= 20 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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 Record created 2026-08-07, last modified 2026-08-07


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