Journal Article DZNE-2021-01304

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Quantitative evaluation of prospective motion correction in healthy subjects at 7T MRI.

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2022
Wiley-Liss New York, NY [u.a.]

Magnetic resonance in medicine 87(2), 646-657 () [10.1002/mrm.28998]

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Abstract: Quantitative assessment of prospective motion correction (PMC) capability at 7T MRI for compliant healthy subjects to improve high-resolution images in the absence of intentional motion.Twenty-one healthy subjects were imaged at 7 T. They were asked not to move, to consider only unintentional motion. An in-bore optical tracking system was used to monitor head motion and consequently update the imaging volume. For all subjects, high-resolution T1 (3D-MPRAGE), T2 (2D turbo spin echo), proton density (2D turbo spin echo), and T 2 ∗ (2D gradient echo) weighted images were acquired with and without PMC. The images were evaluated through subjective and objective analysis.Subjective evaluation overall has shown a statistically significant improvement (5.5%) in terms of image quality with PMC ON. In a separate evaluation of every contrast, three of the four contrasts (T1 , T2 , and proton density) have shown a statistically significant improvement (9.62%, 9.85%, and 9.26%), whereas the fourth one ( T 2 ∗ ) has shown improvement, although not statistically significant. In the evaluation with objective metrics, average edge strength has shown an overall improvement of 6% with PMC ON, which was statistically significant; and gradient entropy has shown an overall improvement of 2%, which did not reach statistical significance.Based on subjective assessment, PMC improved image quality in high-resolution images of healthy compliant subjects in the absence of intentional motion for all contrasts except T 2 ∗ , in which no significant differences were observed. Quantitative metrics showed an overall trend for an improvement with PMC, but not all differences were significant.

Keyword(s): Artifacts (MeSH) ; Brain: diagnostic imaging (MeSH) ; Healthy Volunteers (MeSH) ; Humans (MeSH) ; Image Processing, Computer-Assisted (MeSH) ; Imaging, Three-Dimensional (MeSH) ; Magnetic Resonance Imaging (MeSH) ; Motion (MeSH) ; Prospective Studies (MeSH) ; PMC ; high-resolution structural MRI ; image quality assessment ; optical motion tracking system ; ultrahigh field

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Note: (CC BY-NC)

Contributing Institute(s):
  1. Clinical Neurophysiology and Memory (AG Düzel)
Research Program(s):
  1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2022
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Medline ; Creative Commons Attribution-NonCommercial CC BY-NC 4.0 ; OpenAccess ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; DEAL Wiley ; Essential Science Indicators ; IF < 5 ; JCR ; NationallizenzNationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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 Record created 2021-11-17, last modified 2024-03-20


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