Dataset

DZNE-2023-00239

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dataset: USP9X phosphopeptide mapping

Gloeckner, C. J. (Last author)DZNE*

2020
PRoteomics IDEntifications Database

Abstract: We previously identified the deubiquitylase USP9X as a G2/M-specific CDC14B interactor (PXD012732). The functional connection of these proteins has been further investigated by a quantitative comparison of USP9X phosphorylation in WT vs CDC14B-overexpressing HEK 293Tcells (ATCC® CRL-3216™). The approach identified USP9X serine 2563 as a specific CDC14B target. Phosphorylation at USP9XS2563 has been confirmed by in-house phosphospecific antibodies.

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Contributing Institute(s):

1. Functional Neuroproteomics and Translational Biomarkers in Neurodegenerative Diseases (AG Gloeckner)

Research Program(s):

1. 352 - Disease Mechanisms (POF4-352) (POF4-352)

Appears in the scientific report 2020

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Linked articles:

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Dietachmayr, M. ; Rathakrishnan, A. ; Karpiuk, O. ; von Zweydorf, F.DZNE* ; Engleitner, T. ; Fernández-Sáiz, V. ; Schenk, P. ; Ueffing, M. ; Rad, R. ; Eilers, M. ; Gloeckner, C. J.DZNE* ; Clemm von Hohenberg, K. (Corresponding author) ; Bassermann, F.
Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival.
Nature Communications 11(1), 1268 (2020) [10.1038/s41467-020-15059-5]2020   Files  Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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