| Home > Publications Database > Hierarchical network analysis of behavior and neuronal population activity |
| Contribution to a conference proceedings/Contribution to a book | DZNE-2023-01140 |
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2019
Cognitive Computational Neuroscience Brentwood, Tennessee, USA
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Please use a persistent id in citations: doi:10.32470/CCN.2019.1261-0
Abstract: Recording of neuronal population activity in behaving animals is becoming increasingly popular. Computationalmarkerless annotation tools allow for tracking of animal body-parts throughout the experiment. However, thequestion remains of how to cross-correlate the extractedbehavioral data with the simultaneously acquired neuronal population activity, when both datasets are of highdimensionality. Here we propose a combined analysis,where the behavioral data is clustered into discrete statesusing a deep learning model and the occurrence of eachstate is correlated to clusters of neuronal activity. Wethen model the relationship between behavioral states asa network, where related states are hierarchically groupedwhile the similarity between their neuronal correlates ismaximized. This type of analysis allows for hierarchicalexploration of the bidirectional relationship between behavior and its neuronal correlates at different temporalscales.
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