AG Fluhrer

Signal Peptide Peptidases as Models for γ-Secretase Also known as:AG Fluhrer; Signalpeptid Peptidasen als Modelle für γ-Sekretase
IDI:(DE-2719)1110000-2

M DZNE

Recent Publications

All known publications ...
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Signaling Functions of Intramembrane Aspartyl-Proteases.
Frontiers in Cardiovascular Medicine 7, 591787 () [10.3389/fcvm.2020.591787] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Non-canonical Shedding of TNFα by SPPL2a Is Determined by the Conformational Flexibility of Its Transmembrane Helix.
iScience 23(12), 101775 () [10.1016/j.isci.2020.101775] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Physiological functions of SPP/SPPL intramembrane proteases
Cellular and molecular life sciences 77(15), 2959-2979 () [10.1007/s00018-020-03470-6] OpenAccess  Download fulltext Files  Download fulltextFulltext Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
Journal of experimental medicine 216(4), 807-830 () [10.1084/jem.20171438] pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Signal Peptide Peptidase-Like 2c (SPPL2c) impairs vesicular transport and cleaves SNARE proteins.
EMBO reports 20(3), e46451 () [10.15252/embr.201846451] pmc  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban.
EMBO reports 20(3), e46449 () [10.15252/embr.201846449] pmc  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Proteolytic ectodomain shedding of membrane proteins in mammals-hardware, concepts, and recent developments.
The EMBO journal 37(15), e99456 () [10.15252/embj.201899456] pmc  Download fulltext Files  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Signal peptide peptidase and SPP-like proteases - Possible therapeutic targets?
Biochimica et biophysica acta / Molecular cell research 1864(11), 2169-2182 () [10.1016/j.bbamcr.2017.06.007]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Latest emerging functions of SPP/SPPL intramembrane proteases.
European journal of cell biology 96(5), 372-382 () [10.1016/j.ejcb.2017.03.002]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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CLN5 is cleaved by members of the SPP/SPPL family to produce a mature soluble protein.
Experimental cell research 357(1), 40-50 () [10.1016/j.yexcr.2017.04.024] BibTeX | EndNote: XML, Text | RIS

All known publications ...
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 Record created 2020-02-18, last modified 2024-09-06



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