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AG Fluhrer
Signal Peptide Peptidases as Models for γ-Secretase Also known as:AG Fluhrer; Signalpeptid Peptidasen als Modelle für γ-Sekretase| ID | I:(DE-2719)1110000-2 |
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Journal Article
Signaling Functions of Intramembrane Aspartyl-Proteases.
Frontiers in Cardiovascular Medicine 7, 591787 (2020) [10.3389/fcvm.2020.591787]
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Journal Article
Non-canonical Shedding of TNFα by SPPL2a Is Determined by the Conformational Flexibility of Its Transmembrane Helix.
iScience 23(12), 101775 (2020) [10.1016/j.isci.2020.101775]
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Journal Article
Physiological functions of SPP/SPPL intramembrane proteases
Cellular and molecular life sciences 77(15), 2959-2979 (2020) [10.1007/s00018-020-03470-6]
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Journal Article
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
Journal of experimental medicine 216(4), 807-830 (2019) [10.1084/jem.20171438]
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Journal Article
Signal Peptide Peptidase-Like 2c (SPPL2c) impairs vesicular transport and cleaves SNARE proteins.
EMBO reports 20(3), e46451 (2019) [10.15252/embr.201846451]
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The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban.
EMBO reports 20(3), e46449 (2019) [10.15252/embr.201846449]
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Journal Article (Review Article)
Proteolytic ectodomain shedding of membrane proteins in mammals-hardware, concepts, and recent developments.
The EMBO journal 37(15), e99456 (2018) [10.15252/embj.201899456]
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Journal Article (Review Article)
Signal peptide peptidase and SPP-like proteases - Possible therapeutic targets?
Biochimica et biophysica acta / Molecular cell research 1864(11), 2169-2182 (2017) [10.1016/j.bbamcr.2017.06.007]
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Journal Article (Review Article)
Latest emerging functions of SPP/SPPL intramembrane proteases.
European journal of cell biology 96(5), 372-382 (2017) [10.1016/j.ejcb.2017.03.002]
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Journal Article
CLN5 is cleaved by members of the SPP/SPPL family to produce a mature soluble protein.
Experimental cell research 357(1), 40-50 (2017) [10.1016/j.yexcr.2017.04.024]
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