Journal Article

DZNE-2021-00749

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Evolution of psychosocial burden and psychiatric symptoms in patients with psychiatric disorders during the Covid-19 pandemic.

Belz, M. ; Hessmann, P. ; Vogelgsang, J. ; Schmidt, U. ; Ruhleder, M. ; Signerski-Krieger, J. ; Radenbach, K. ; Trost, S. ; Schott, B. H.DZNE* ; Wiltfang, J.DZNE* ; Wolff-Menzler, C. ; Bartels, C. (Corresponding author)Extern*

2022
Springer Heidelberg

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Please use a persistent id in citations: doi:10.1007/s00406-021-01268-6

Abstract: The Covid-19 pandemic highly impacts mental health worldwide. Patients with psychiatric disorders are a vulnerable risk population for worsening of their condition and relapse of symptoms. This study investigates the pandemic-related course of psychosocial burden in patients with pre-existing mental disorders. With the newly developed Goettingen psychosocial Burden and Symptom Inventory (Goe-BSI) psychosocial burden has been traced retrospectively (1) before the pandemic (beginning of 2020), (2) at its beginning under maximum lockdown conditions (March 2020), and (3) for the current state after maximum lockdown conditions (April/May 2020). The Goe-BSI also integrates the Adjustment Disorder New Module (ADNM-20), assesses general psychiatric symptoms, and resilience. A total of 213 patients covering all major psychiatric disorders (ICD-10 F0-F9) were interviewed once in the time range from April, 24th until May 11th, 2020. Across all diagnoses patients exhibited a distinct pattern with an initial rise followed by a decline of psychosocial burden (p < 0.001, partial η2 = 0.09; Bonferroni-corrected pairwise comparisons between all three time-points: p < 0.05 to 0.001). Female gender and high ADNM-20 scores were identified as risk factors for higher levels and an unfavorable course of psychosocial burden over time. Most psychiatric symptoms remained unchanged. Trajectories of psychosocial burden vary in parallel to local lockdown restrictions and seem to reflect an adaptive stress response. For female patients with pre-existing mental disorders and patients with high-stress responses, timely and specific treatment should be scheduled. With the continuation of the pandemic, monitoring of long-term effects is of major importance, especially when long incubation times for the development of mental health issues are considered.

Keyword(s): COVID-19: epidemiology (MeSH) ; COVID-19: psychology (MeSH) ; Cost of Illness (MeSH) ; Female (MeSH) ; Humans (MeSH) ; Mental Disorders: epidemiology (MeSH) ; Mental Disorders: psychology (MeSH) ; Pandemics (MeSH) ; Retrospective Studies (MeSH) ; Adjustment disorder ; Coronavirus ; Mental health ; Psychosocial stress ; SARS-CoV-2

Note: (CC BY)

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Contributing Institute(s):

1. Epigenetics and Systems Medicine in Neurodegenerative Diseases (AG Fischer 1)
2. Alzheimer Biomarker and Clinical Study Group (AG Wiltfang)

Research Program(s):

1. 352 - Disease Mechanisms (POF4-352) (POF4-352)
2. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2022

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Database coverage:
; ; ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; DEAL Springer ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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