Journal Article (Review Article)

DZNE-2022-00130

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Physical Activity Interventions and Their Effects on Cognitive Function in People with Dementia: A Systematic Review and Meta-Analysis.

Cardona, M. I. (First author)DZNE* ; Afi, A.DZNE* ; Lakicevic, N. ; Thyrian, J. R. (Last author)DZNE*

2021
MDPI AG Basel

This record in other databases:    

Please use a persistent id in citations: doi:10.3390/ijerph18168753

Abstract: Physical activity (PA) has emerged as an alternative nonpharmacological approach to effectively address the effects of dementia. The primary aim was to identify and summarize PA interventions and their effects on cognitive function among persons with dementia (PwD).A systematic review was conducted with a meta-analysis using different electronic databases, such as PubMed, Embase, APA PsycNET, and the Web of Science. The identified and selected studies were randomized controlled trials (RCTs) that were written in English, published between 2000 and 2020, and implemented among PwD who received a PA intervention and whose cognitive function was measured at baseline and during a follow-up.Twenty-two PA intervention studies met the eligibility criteria and showed a medium-size effect on the cognitive function of PwD, 0.4803 (95% CI = 0.1901-0.7704), with a high percentage of heterogeneity (I2 = 86%, p ≤ 0.0001). Moreover, this review complements other reviews by including eight studies that have not previously been considered. Overall, studies have methodological limitations. However, six studies implemented in the past five years have shown more robust methodological designs, including larger sample sizes and more comprehensive measurement tools.It is not yet possible to draw a conclusion on the ideal PA intervention for this population due to the high proportion of heterogeneity within the included studies. More emphasis is needed on the intensity of PA monitoring and adherence to such programs.

Keyword(s): Cognition (MeSH) ; Dementia: therapy (MeSH) ; Exercise (MeSH) ; Humans (MeSH) ; cognitive function ; dementia ; physical activity

Note: (CC BY)

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Contributing Institute(s):

1. Interventional Health Care Research (IHCR) (AG Thyrian)
2. Translational Health Care Research (AG Hoffmann)

Research Program(s):

1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2021

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Database coverage:
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