Journal Article

DZNE-2022-00757

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Processing speed, but not working memory or global cognition, is associated with pupil diameter during fixation.

Coors, A. (First author)DZNE* ; Breteler, M.DZNE* ; Ettinger, U.

2022
Wiley-Blackwell Malden, Mass. [u.a.]

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Please use a persistent id in citations: doi:10.1111/psyp.14089

Abstract: Mean pupil size during fixation has been suggested to reflect interindividual differences in working memory and fluid intelligence. However, due to small samples with limited age range (17-35 years) and suboptimal light conditions in previous studies, these associations are still controversial and it is unclear whether they are observed at older ages. Therefore, we assessed whether interindividual differences in cognitive performance are reflected in pupil diameter during fixation and whether these associations are age-dependent. We analyzed pupillometry and cognition data of 4560 individuals aged 30-95 years of the community-based Rhineland Study. Pupillometry data were extracted from a one-minute fixation task. The cognitive test battery included tests of oculomotor control, working memory, episodic verbal memory, processing speed, executive function, and crystallized intelligence. For data analysis, we used multivariable regression models. Working memory and global cognition were not associated with pupil diameter during fixation. Better processing speed performance was associated with larger pupil diameter during fixation. Associations between cognition and pupil diameter during fixation hardly varied with age, but pupil diameter during fixation declined linearly with age (adjusted decline: 0.33 mm per 10 years of age). There were no significant sex differences in pupil size. We conclude that interindividual differences in mean pupil diameter during fixation may partly reflect interindividual differences in the speed of processing and response generation. We could not confirm that interindividual differences in working memory and fluid intelligence are reflected in pupil size during fixation; however, our sample differed in age range from previous studies.

Keyword(s): Adolescent (MeSH) ; Adult (MeSH) ; Child (MeSH) ; Cognition: physiology (MeSH) ; Female (MeSH) ; Humans (MeSH) ; Intelligence: physiology (MeSH) ; Male (MeSH) ; Memory, Short-Term: physiology (MeSH) ; Pupil: physiology (MeSH) ; Young Adult (MeSH) ; age ; cognition ; cohort studies ; intelligence ; pupillometry

Note: (CC BY)

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Contributing Institute(s):

1. Population Health Sciences (AG Breteler)

Research Program(s):

1. 354 - Disease Prevention and Healthy Aging (POF4-354) (POF4-354)

Experiment(s):

1. Rhineland Study / Bonn

Appears in the scientific report 2022

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Database coverage:
; ; ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Current Contents - Social and Behavioral Sciences ; DEAL Wiley ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Social Sciences Citation Index ; Web of Science Core Collection

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